Publications of M. S. Hipp

Hipp, M. S.; Hartl, F. U.: Interplay of proteostasis capacity and Pprotein aggregation: Implications for cellular function and disease. Journal of Molecular Biology 436 (14), 168615 (2024)

Saha, I.; Yuste-Checa, P.; Padilha, M. D. S.; Guo, Q.; Körner, R.; Holthusen, H.; Trinkaus, V. A.; Dudanova, I.; Fernandez-Busnadiego, R.; Baumeister, W. et al.; Sanders, D. W.; Gautam, S.; Diamond, M. I.; Hartl, F. U.; Hipp, M. S.: The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system. Nature Communications 14 (1), 560 (2023)

Riemenschneider, H.; Guo, Q.; Bader, J. M.; Frottin, F.; Farny, D.; Kleinberger, G.; Haass, C.; Mann, M.; Hartl, F. U.; Baumeister, W. et al.; Hipp, M. S.; Meissner, F.; Fernandez-Busnadiego, R.; Edbauer, D.: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. EMBO Reports 23 (6), e53890 (2022)

Blumenstock, S.; Schulz-Trieglaff, K.; Voelkl, K.; Bolender, A.-L.; Lapios, P.; Lindner, J.; Hipp, M. S.; Hartl, F. U.; Klein, R.; Dudanova, I.: Fluc-EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease. EMBO Journal 40 (19), e107260 (2021)

Frottin, F.; Perez-Berlanga, M.; Hartl, F. U.; Hipp, M. S.: Multiple pathways of toxicity induced by c9orf72 dipeptide repeat aggregates and G(4)C(2) RNA in a cellular model. eLife 10, e62718 (2021)

Trinkaus, V. A.; Riera-Tur, I.; Martinez Sanchez, A.; Bäuerlein, F. J. B.; Guo, Q.; Arzberger, T.; Baumeister, W.; Dudanova, I.; Hipp, M. S.; Hartl, F. U. et al.; Fernandez-Busnadiego, R.: In situ architecture of neuronal alpha-Synuclein inclusions. Nature Communications 12 (1), 2110 (2021)

Yuste-Checa, P.; Trinkaus, V. A.; Riera-Tur, I.; Imamoglu, R.; Schaller, T. F.; Wang, H.; Dudanova, I.; Hipp, M. S.; Bracher, A.; Hartl, F. U.: The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model. Nature Communications 12 (1), 4863 (2021)

Bie, A. S.; Coemert, C.; Körner, R.; Corydon, T. J.; Palmfeldt, J.; Hipp, M. S.; Hartl, F. U.; Bross, P.: An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space. Cell Stress & Chaperones 25, pp. 407 - 416 (2020)

Broch Trentini, D.; Pecoraro, M.; Tiwary, S.; Cox, J.; Mann, M.; Hipp, M. S.; Hartl, F. U.: Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (8), pp. 4099 - 4108 (2020)

Khosravi, B.; LaClair, K. D.; Riemenschneider, H.; Zhou, Q.; Frottin, F.; Mareljic, N.; Czuppa, M.; Farny, D.; Hartmann, H.; Michaelsen, M. et al.; Arzberger, T.; Hartl, F. U.; Hipp, M. S.; Edbauer, D.: Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD. EMBO JOURNAL 39 (8), e102811 (2020)

Frottin, F.; Schueder, F.; Tiwary, S.; Gupta, R.; Körner, R.; Schlichthaerle, T.; Cox, J.; Jungmann, R.; Hartl, F. U.; Hipp, M. S.: The nucleolus functions as a phase-separated protein quality control compartment. Science 365 (6451), pp. 342 - 347 (2019)

Hipp, M. S.; Kasturi, P.; Hartl, F. U.: The proteostasis network and its decline in ageing. Nature Reviews Molecular Cell Biology 20, pp. 421 - 435 (2019)

Jayaraj, G. G.; Hipp, M. S.; Hartl, F. U.: Functional Modules of the Proteostasis Network. Cold Spring Harbor Perspectives in Biology (2019)

van Well, E. M.; Bader, V.; Patra, M.; Sanchez-Vicente, A.; Meschede, J.; Furthmann, N.; Schnack, C.; Blusch, A.; Longworth, J.; Petrasch-Parwez, E. et al.; Mori, K.; Arzberger, T.; Truembach, D.; Angersbach, L.; Showkat, C.; Sehr, D. A.; Berlemann, L. A.; Goldmann, P.; Clement, A. M.; Behl, C.; Woerner, A. C.; Saft, C.; Wurst, W.; Haass, C.; Ellrichmann, G.; Gold, R.; Dittmar, G.; Hipp, M. S.; Hartl, F. U.; Tatzelt, J.; Winklhofer, K. F.: A protein quality control pathway regulated by linear ubiquitination. EMBO Journal 38 (9), e100730 (2019)

Vincenz-Donnelly, L.; Holthusen, H.; Körner, R.; Hansen, E. C.; Presto, J.; Johansson, J.; Sawarkar, R.; Hartl, F. U.; Hipp, M. S.: High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins. The EMBO Journal 37 (3), pp. 337 - 350 (2018)

Gruber, A.; Hornburg, D.; Antonin, M.; Krahmer, N.; Collado, J.; Schaffer, M.; Zubaite, G.; Luechtenborg, C.; Sachsenheimer, T.; Bruegger, B. et al.; Mann, M.; Baumeister, W.; Hartl, F. U.; Hipp, M. S.; Fernandez-Busnadiego, R.: Molecular and structural architecture of polyQ aggregates in yeast. Proceedings of the National Academy of Sciences of the United States of America 115 (15), pp. E3446 - E3453 (2018)

Guo, Q.; Lehmer, C.; Martinez Sanchez, A.; Rudack, T.; Beck, F.; Hartmann, H.; Perez-Berlanga, M.; Frottin, F.; Hipp, M. S.; Hartl, F. U. et al.; Edbauer, D.; Baumeister, W.; Fernandez-Busnadiego, R.: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell 172 (4), pp. 696 - 705.e12 (2018)

Hosp, F.; Gutiérrez-Ángel, S.; Schaefer, M. H.; Cox, J.; Meissner, F.; Hipp, M. S.; Hartl, F. U.; Klein, R.; Dudanova, I.; Mann, M.: Spatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function. Cell Reports 21 (8), pp. 2291 - 2303 (2017)

Bäuerlein, F. J. B.; Saha, I.; Mishra, A.; Kalemanov, M.; Martinez-Sanchez, A.; Klein, R.; Dudanova, I.; Hipp, M. S.; Hartl, F. U.; Baumeister, W. et al.; Fernandez-Busnadiego, R.: In Situ Architecture and Cellular Interactions of PolyQ Inclusions. Cell 171 (1), e10, pp. 179 - 187.e10 (2017)

De Smet, F.; Rubio, M. S.; Hompes, D.; Naus, E.; De Baets, G.; Langenberg, T.; Hipp, M. S.; Houben, B.; Claes, F.; Charbonneau, S. et al.; Blanco, J. D.; Plaisance, S.; Ramkissoon, S.; Ramkissoon, L.; Simons, C.; van den Brandt, P.; Weijenberg, M.; Van England, M.; Lambrechts, S.; Amant, F.; D'Hoore, A.; Ligon, K. L.; Sagaert, X.; Schymkowitz, J.; Rousseau, F.: Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation. Journal of Pathology: an Official Journal of the Pathological Society 242 (1), pp. 24 - 38 (2017)