Publications of Martin Steger

Thielert, M.; Itang, E. C. M.; Ammar, C.; Rosenberger, F. A.; Bludau, I.; Schweizer, L.; Nordmann, T. M.; Skowronek, P.; Wahle, M.; Zeng, W.-F. et al.; Zhou, X.-X.; Brunner, A.-D.; Richter, S.; Levesque, M. P.; Theis, F. J.; Steger, M.; Mann, M.: Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel. Molecular Systems Biology 19 (9), e1150 (2023)

Nagao, H.; Cai, W.; Brandao, B. B.; Wewer Albrechtsen, N. J.; Steger, M.; Gattu, A. K.; Pan, H.; Dreyfuss, J. M.; Wunderlich, F. T.; Mann, M. et al.; Kahn, C. R.: Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling. The Journal of Clinical Investigation 133 (4), e161472 (2023)

Steger, M.; Karayel, Ö.; Demichev, V.: Ubiquitinomics: History, methods, and applications in basic research and drug discovery. Proteomics 22 (15-16), e2200074 (2022)

Takahashi, M.; Lio, C.-W. J.; Campeau, A.; Steger, M.; Ay, F.; Mann, M.; Gonzalez, D. J.; Jain, M.; Sharma, S.: The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-beta pathway. Nature Immunology 22, pp. 485 - 496 (2021)

Nagao, H.; Cai, W.; Wewer Albrechtsen, N. J.; Steger, M.; Batista, T. M.; Pan, H.; Dreyfuss, J. M.; Mann, M.; Kahn, C. R.: Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains. Proceedings of the National Academy of Sciences of the United States of America 118 (17), e2019474118 (2021)

Hecht, T. K.-H.; Blank, B.; Steger, M.; Lopez, V.; Beck, G.; Ramazanov, B.; Mann, M.; Tagliabracci, V.; von Blume, J.: Fam20C regulates protein secretion by Cab45 phosphorylation. JOURNAL OF CELL BIOLOGY 219 (6), e201910089 (2020)

Karayel, Ö.; Tonelli, F.; Virreira Winter, S.; Geyer, P. E.; Fan, Y.; Sammler, E. M.; Alessi, D. R.; Steger, M.; Mann, M.: Accurate MS-based Rab10 Phosphorylation Stoichiometry Determination as Readout for LRRK2 Activity in Parkinson's Disease. Molecular and Cellular Proteomics 19 (9), pp. 1546 - 1560 (2020)

Sakaguchi, M.; Cai, W.; Wang, C.-H.; Cederquist, C. T.; Damasio, M.; Homan, E. P.; Batista, T.; Ramirez, A. K.; Gupta, M. K.; Steger, M. et al.; Albrechtsen, N. J. W.; Singh, S. K.; Araki, E.; Mann, M.; Enerback, S.; Kahn, C. R.: FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism. Nature Communications 10, 1582 (2019)

Dhekne, H. S.; Yanatori, I.; Gomez, R. C.; Tonelli, F.; Diez, F.; Schule, B.; Steger, M.; Alessi, D. R.; Pfeffer, S. R.: A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. eLife 7, e40202 (2018)

Krahmer, N.; Najafi, B.; Schueder, F.; Quagliarini, F.; Steger, M.; Seitz, S.; Kasper, R.; Salinas, F.; Cox, J.; Uhlenhaut, N. H. et al.; Walther, T. C.; Jungmann, R.; Zeigerer, A.; Borner, G. H. H.; Mann, M.: Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis. Developmental Cell 47 (2), pp. 205 - 221.e7 (2018)

Lis, P.; Burel, S.; Steger, M.; Mann, M.; Brown, F.; Diez, F.; Tonelli, F.; Holton, J. L.; Ho, P. W.; Ho, S.-L. et al.; Chou, M.-Y.; Polinski, N. K.; Martinez, T. N.; Davies, P.; Alessi, D. R.: Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase. Biochemical Journal 475, pp. 1 - 22 (2018)

Steger, M.; Diez, F.; Dhekne, H. S.; Lis, P.; Nirujogi, R. S.; Karayel, O.; Tonelli, F.; Martinez, T. N.; Lorentzen, E.; Pfeffer, S. R. et al.; Alessi, D. R.; Mann, M.: Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. eLife 6, e31012 (2017)

Steger, M.; Tonelli, F.; Ito, G.; Davies, P.; Trost, M.; Vetter, M.; Wachter, S.; Lorentzen, E.; Duddy, G.; Wilson, S. et al.; Baptista, M. A. S.; Fiske, B. K.; Fell, M. J.; Morrow, J. A.; Reith, A. D.; Alessi, D. R.; Mann, M.: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases. ELIFE 5, e12813 (2016)

Skotte, N. H.; Geyer, P. E.; Steger, M.; Treit, P. V.; Voytik, E.; Hellem, M. N.; Nielsen, J. E.; Mann, M.: Quality control for plasma and cerebrospinal fluid samples using mass spectrometry. In Journal of Neurology, Neurosurgery & Psychiatry, 89, pp. A31 - A32. Plenary Meeting of the European-Huntington's-Disease-Network (EHDN), Vienna, AUSTRIA. British Medical Association, London (2018)