Publications of Reinhard Fässler

Chen, N.-P.; Sun, Z.; Fässler, R.: The Kank family proteins in adhesion dynamics. Current Opinion in Cell Biology 54, pp. 130 - 136 (2018)

Gerard, C.; Hubeau, C.; Carnet, O.; Bellefroid, M.; Sounni, N. E.; Blacher, S.; Bendavid, G.; Moser, M.; Fässler, R.; Noel, A. et al.; Cataldo, D.; Rocks, N.: Microenvironment-derived ADAM28 prevents cancer dissemination. Oncotarget 9 (98), pp. 37185 - 37199 (2018)

Moretti, F. A.; Klapproth, S.; Ruppert, R.; Margraf, A.; Jasmin, W.; Pick, R.; Scheiermann, C.; Sperandio, M.; Fässler, R.; Moser, M.: Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. eLife 7, e35816 (2018)

Wujak, L.; Böttcher, R. T.; Pak, O.; Frey, H.; El Agha, E.; Chen, Y.; Schmitt, S.; Bellusci, S.; Schaefer, L.; Weissmann, N. et al.; Fässler, R.; Wygrecka, M.: Low density lipoprotein receptor-related protein 1 couples beta 1 integrin activation to degradation. Cellular and Molecular Life Sciences 75 (9), pp. 1671 - 1685 (2018)

Ringer, P.; Colo, G.; Fässler, R.; Grashoff, C.: Sensing the mechano-chemical properties of the extracellular matrix. Matrix Biology 64, pp. 6 - 16 (2017)

Strohmeyer, N.; Bharadwaj, M.; Costell, M.; Fässler, R.; Müller, D. J.: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second. Nature Materials 16, pp. 1262 - 1270 (2017)

Bharadwaj, M.; Strohmeyer, N.; Colo, G. P.; Helenius, J.; Beerenwinkel, N.; Schiller, H. B.; Fässler, R.; Müller, D. J.: αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. Nature Communications 8, 14348 (2017)

Böttcher, R. T.; Sun, Z.; Fässler, R.: A forceful connection: mechanoregulation of oncogenic YAP. The EMBO Journal 36 (17), pp. 2467 - 2469 (2017)

Böttcher, R. T.; Veelders, M.; Rombaut, P.; Faix, J.; Theodosiou, M.; Stradal, T. E.; Rottner, K.; Zent, R.; Herzog, F.; Fässler, R.: Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. Journal of Cell Biology 216 (11), pp. 3785 - 3798 (2017)

Kammerer, P.; Aretz, J.; Fässler, R.: Lucky kindlin: A cloverleaf at the integrin tail. Proceedings of the National Academy of Sciences of the United States of America 114 (35), pp. 9234 - 9236 (2017)

Mathew, S.; Palamuttam, R. J.; Mernaugh, G.; Ramalingam, H.; Lu, Z.; Zhang, M.-Z.; Ishibe, S.; Critchley, D. R.; Fässler, R.; Pozzi, A. et al.; Sanders, C. R.; Carroll, T. J.; Zent, R.: Talin regulates integrin beta 1-dependent and -independent cell functions in ureteric bud development. Development 144 (22), pp. 4148 - 4158 (2017)

Lu, Z.; Mathew, S.; Chen, J.; Hadziselimovic, A.; Palamuttam, R.; Hudson, B. G.; Fässler, R.; Pozzi, A.; Sanders, C. R.; Zent, R.: Implications of the differing roles of the beta 1 and beta 3 transmembrane and cytosplasmic domains for integrin function. eLife 5, e18633 (2016)

Cerikan, B.; Shaheen, R.; Colo, G. P.; Glaesser, C.; Hata, S.; Knobeloch, K.-P.; Alkuraya, F. S.; Faessler, R.; Schiebel, E.: Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator. Developmental Cell 39 (1), pp. 28 - 43 (2016)

Rognoni, E.; Ruppert, R.; Fässler, R.: The kindlin family: functions, signaling properties and implications for human disease. Journal of Cell Science 129 (1), pp. 17 - 27 (2016)

Cheah, M.; Andrews, M. R.; Chew, D. J.; Moloney, E. B.; Verhaagen, J.; Fässler, R.; Fawcett, J. W.: Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord. The Journal of Neuroscience 36 (27), pp. 7283 - 7297 (2016)

Geiger, B.; Fässler, R.: Introduction to the ECR special issue, "Mechanosensing via Cell-Matrix Adhesions". EXPERIMENTAL CELL RESEARCH 343 (1), pp. 1 - 2 (2016)

Hermann, M.-R.; Jakobson, M.; Colo, G. P.; Rognoni, E.; Jakobson, M.; Kupatt, C.; Posern, G.; Fässler, R.: Integrins synergise to induce expression of the MRTF-A-SRF target gene ISG15 for promoting cancer cell invasion. JOURNAL OF CELL SCIENCE 129 (7), pp. 1391 - 1403 (2016)

Lukjanenko, L.; Jung, M. J.; Hegde, N.; Perruisseau-Carrier, C.; Migliavacca, E.; Rozo, M.; Karaz, S.; Jacot, G.; Schmidt, M.; Li, L. et al.; Metairon, S.; Raymond, F.; Lee, U.; Sizzano, F.; Wilson, D. H.; Dumont, N. A.; Palini, A.; Fässler, R.; Steiner, P.; Descombes, P.; Rudnicki, M. A.; Fan, C.-M.; von Maltzahn, J.; Feige, J. N.; Bentzinger, C. F.: Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice. Nature Medicine 22 (8), pp. 897 - 905 (2016)

Sun, Z.; Guo, S. S.; Fässler, R.: Integrin-mediated mechanotransduction. The Journal of Cell Biology: JCB 215 (4), pp. 445 - 456 (2016)

Sun, Z.; Tseng, H.-Y.; Tan, S.; Senger, F.; Kurzawa, L.; Dedden, D.; Mizuno, N.; Wasik, A. A.; Thery, M.; Dunn, A. R. et al.; Fässler, R.: Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation. Nature Cell Biology 18 (9), pp. 941 - 953 (2016)