Publications of H. Brandstetter

Goettig, P.; Brandstetter, H.; Groll, M.; Göhring, W.; Konarev, P. V.; Svergun, D. I.; Huber, R.; Kim, J. S.: X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum. Journal of Biological Chemistry 280 (39), pp. 33387 - 33396 (2005)

Messerschmidt, A.; Macieira, S.; Velarde, M.; Badeker, M.; Benda, C.; Jestel, A.; Brandstetter, H.; Neuefeind, T.; Blaesse, M.: Crystal structure of the catalytic domain of human atypical protein kinase C-iota reveals interaction mode of phosphorylation site in turn motif. Journal of Molecular Biology 352 (4), pp. 918 - 931 (2005)

Kyrieleis, O. J. P.; Goettig, P.; Kiefersauer, R.; Huber, R.; Brandstetter, H.: Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations. Journal of Molecular Biology 349 (4), pp. 787 - 800 (2005)

Groll, M.; Bochtler, M.; Brandstetter, H.; Clausen, T.; Huber, R.: Molecular machines for protein degradation. ChemBioChem 6 (2), pp. 222 - 256 (2005)

Brandstetter, H.; Scheer, M.; Heinekamp, C.; Gippner-Steppert, C.; Loge, O.; Ruprecht, L.; Thull, B.; Wagner, R.; Wilhelm, R.; Scheuber, H. P.: Performance evaluation of IVC systems. Laboratory Animals 39 (1), pp. 40 - 44 (2005)

Ksiazek, D.; Brandstetter, H.; Israel, L.; Bourenkov, G. P.; Katchalova, G.; Janssen, K. P.; Bartunik, H. D.; Noegel, A. A.; Schleicher, M.; Holak, T. A.: Structure of the n-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum. Structure 11 (9), pp. 1171 - 1178 (2003)

Engel, M.; Hoffmann, T.; Wagner, L.; Wermann, M.; Heiser, U.; Kiefersauer, R.; Huber, R.; Bode, W.; Demuth, H. U.; Brandstetter, H.: The crystal structure of dipeptidyl peptidase IV(CD26) reveals its functional regulation and enzymatic mechanism. Proceedings of the National Academy of Sciences of the United States of America 100 (9), pp. 5063 - 5068 (2003)

Groll, M.; Brandstetter, H.; Bartunik, H.; Bourenkow, G.; Huber, R.: Investigations on the maturation and regulation of archaebacterial proteasomes. Journal of Molecular Biology 327 (1), pp. 75 - 83 (2003)

Sichler, K.; Kopetzki, E.; Huber, R.; Bode, W.; Hopfner, K. P.; Brandstetter, H.: Physiological fIXa activation involves a cooperative conformational rearrangement of the 99-loop. Journal of Biological Chemistry 278 (6), pp. 4121 - 4126 (2003)

Kim, J. S.; Groll, M.; Musiol, H.-J.; Behrendt, R.; Kaiser, M.; Moroder, L.; Huber, R.; Brandstetter, H.: Navigation inside a protease: Substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum. Journal of Molecular Biology 324 (5), pp. 1041 - 1050 (2002)

Sichler, K.; Hopfner, K. P.; Kopetzki, E.; Huber, R.; Bode, W.; Brandstetter, H.: The influence of residue 190 in the S1 site of trypsin-like serine proteases on substrate selectivity is universally conserved. FEBS Letters 530 (1-3), pp. 220 - 224 (2002)

Goettig, P.; Groll, M.; Kim, J. S.; Huber, R.; Brandstetter, H.: Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism. EMBO Journal 21 (20), pp. 5343 - 5352 (2002)

Sichler, K.; Banner, D. W.; D'Arcy, A.; Hopfner, K. P.; Huber, R.; Bode, W.; Kresse, G. B.; Kopetzki, E.; Brandstetter, H.: Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions. Journal of Molecular Biology 322 (3), pp. 591 - 603 (2002)

Cha, H. J.; Kopetzki, E.; Huber, R.; Lanzendörfer, M.; Brandstetter, H.: Structural basis of the adaptive molecular recognition by MMP9. Journal of Molecular Biology 320 (5), pp. 1065 - 1079 (2002)

Brandstetter, H.; Kim, J. S.; Groll, M.; Göttig, P.; Huber, R.: Structural basis for the processive protein degradation by tricorn protease. Biological Chemistry 383 (7-8), pp. 1157 - 1165 (2002)

Grams, F.; Brandstetter, H.; D'Alo, S.; Geppert, D.; Krell, H. W.; Leinert, H.; Livi, V.; Menta, E.; Oliva, A.; Zimmermann, G.: Pyrimidine-2,4,6-triones: A new effective and selective class of matrix metalloproteinase inhibitors (vol 382, pg 1278, 2001). Biological Chemistry 382 (12), p. 1739 - 1739 (2001)

Bochtler, M.; Groll, M.; Brandstetter, H.; Clausen, T.; Huber, R.: Molecular machines for protein degradation. Protein Degradation. In: Protein Degradation 1, pp. 248 - 287 (Eds. Mayer, R. J.; A., C.; Rechsteiner, M.). Wiley-VCH, Weinheim (2005)