Publications of Wolfram Bode

Debela, M.; Magdolen, V.; Skala, W.; Elsasser, B.; Schneider, E. L.; Craik, C. S.; Biniossek, M. L.; Schilling, O.; Bode, W.; Brandstetter, H. et al.; Goettig, P.: Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Scientific Reports 8, 10705 (2018)

Arolas, J. L.; Broder, C.; Jefferson, T.; Guevara, T.; Sterchi, E. E.; Bode, W.; Stocker, W.; Becker-Pauly, C.; Gomis-Ruth, F. X.: Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane. Proceedings of the National Academy of Sciences of the United States of America 109 (40), pp. 16131 - 16136 (2012)

Tochowicz, A.; Goettig, P.; Visse, R.; Shitomi, Y.; Maskos, K.; Nagase, H.; Bode, W.; Itoh, Y.: Crystal structure of MT1-MMP hemopexin domain: identification of the dimer interface. International Journal of Experimental Pathology 91 (6), pp. A39 - A40 (2010)

Tochowicz, A.; Maskos, K.; Huber, R.; Oltenfreiter, R.; Dive, V.; Yiotakis, A.; Zanda, M.; Pourmotabbed, T.; Bode, W.; Goettig, P.: Corrigendum to "Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side Chain to Selectivity" (Journal of Molecular Biology, vol 371, pg 989, 2007). Journal of Molecular Biology 388 (4), pp. 917 - 918 (2009)

Wisniewska, M.; Goettig, P.; Maskos, K.; Belouski, E.; Winters, D.; Hecht, R.; Black, R.; Bode, W.: Structural determinants of the ADAM inhibition by TIMP-3: Crystal structure of the TACE-N-TIMP-3 complex. Journal of Molecular Biology 381 (5), pp. 1307 - 1319 (2008)

Pallares, I.; Fernandez, D.; Comellas-Bigler, M.; Fernandez-Recio, J.; Ventura, S.; Aviles, F. X.; Bode, W.; Vendrell, J.: Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid). Acta Crystallographica Section D-Biological Crystallography 64, pp. 784 - 791 (2008)

Debela, M.; Beaufort, N.; Magdolen, V.; Schechter, N. M.; Craik, C. S.; Schmitt, M.; Bode, W.; Goettig, P.: Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7. Biological Chemistry 389 (6), pp. 623 - 632 (2008)

Friedrich, R.; Riester, D.; Göttig, P.; Thurk, M.; Schwienhorst, A.; Bode, W.: Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue. European Journal of Medicinal Chemistry 43 (6), pp. 1330 - 1335 (2008)

Barazza, A.; Gotz, M.; Cadamuro, S. A.; Goettig, P.; Willem, M.; Steuber, H.; Kohler, T.; Jestel, A.; Reinemer, P.; Renner, C. et al.; Bode, W.; Moroder, L.: Macrocyclic statine-based inhibitors of BACE-1. ChemBioChem 8 (17), pp. 2078 - 2091 (2007)

Debela, M.; Goettig, P.; Magdolen, V.; Huber, R.; Schechter, N. M.; Bode, W.: Structural basis of the zinc inhibition of human tissue kallikrein 5. Journal of Molecular Biology 373 (4), pp. 1017 - 1031 (2007)

Debela, M.; Hess, P.; Magdolen, V.; Schechter, N. M.; Steiner, T.; Huber, R.; Bode, W.; Goettig, P.: Chymotryptic specificity determinants in the 1.0 angstrom structure of the zinc-inhibited human tissue kallikrein 7. Proceedings of the National Academy of Sciences of the United States of America 104 (41), pp. 16086 - 16091 (2007)

Tochowicz, A.; Maskos, K.; Huber, R.; Oltenfreiter, R.; Dive, V.; Yiotakis, A.; Zanda, M.; Bode, W.; Goettig, P.: Crystal structures of MMP-9 complexes with five inhibitors: Contribution of the flexible arg424 side-chain to selectivity. Journal of Molecular Biology 371 (4), pp. 989 - 1006 (2007)

Keil, C.; Maskos, K.; Than, M.; Hoopes, J.T.; Huber, R.; Tan, F.; Deddish, P.A.; Erdös, E.G.; Skidgel, R.A.; Bode, W.: Crystal Structure of the Human Carboxypeptidase N (Kininase I) Catalytic Domain. Journal of Molecular Biology 366, pp. 504 - 516 (2007)

Debela, M.; Magdolen, V.; Grimminger, V.; Sommerhoff, C.; Messerschmidt, A.; Huber, R.; Friedrich, R.; Bode, W.; Goettig, P.: Crystal structures of human tissue kallikrein 4: Activity modulation by a specific zinc binding site. Journal of Molecular Biology 362 (5), pp. 1094 - 1107 (2006)

Debela, M.; Magdolen, V.; Schechter, N.; Valachova, M.; Lottspeich, F.; Craik, C. S.; Choe, Y.; Bode, W.; Goettig, P.: Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences. Journal of Biological Chemistry 281 (35), pp. 25678 - 25688 (2006)

Steiner, H.; Than, M.; Bode, W.; Haass, C.: Pore-forming scissors? A first structural glimpse of gamma-secretase. Trends in Biochemical Sciences 31 (9), pp. 491 - 493 (2006)

Steinmetzer, T.; Schweinitz, A.; Sturzebecher, A.; Donnecke, D.; Uhland, K.; Schuster, O.; Steinmetzer, P.; Muller, F.; Friedrich, R.; Than, M. E. et al.; Bode, W.; Sturzbecher, J.: Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. Journal of Medicinal Chemistry 49 (14), pp. 4116 - 4126 (2006)

Bode, W.: The structure of thrombin: A janus-headed proteinase. Seminars in Thrombosis and Hemostasis 32 (Suppl. Suppl. 1), pp. 16 - 31 (2006)

Rohr, K. B.; Selwood, T.; Marquardt, U.; Huber, R.; Schechter, N. M.; Bode, W.; Than, M. E.: X-ray structures of free and leupeptin-complexed human alpha I-tryptase mutants: Indication for an alpha ->beta-tryptase transition. Journal of Molecular Biology 357 (1), pp. 195 - 209 (2006)

Bode, W.: Structure and interaction modes of thrombin. Blood Cells Molecules and Diseases 36 (2), pp. 122 - 130 (2006)