Publications of N. Schaschke

Pfizer, J. M.; Assfalg-Machleidt, I.; Machleidt, W.; Moroder, L.; Schaschke, N.: Primed-site probing of papain-like cysteine proteases. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 13 (1-2), pp. 93 - 104 (2007)

Pfizer, J. M.; Assfalg-Machleidt, I.; Machleidt, W.; Moroder, L.; Schaschke, N.: Primed-site Probing of Papain-like Cysteine Proteases. Int. J. Peptide Res. & Therapeut. 13 (1-2), pp. 93 - 104 (2007)

Schaschke, N.; Gabrijelcic-Geiger, D.; Dominik, A.; Sommerhoff, C. P.: Affinity chromatography of tryptases: Design, synthesis and characterization of a novel matrix-bound bivalent inhibitor. ChemBioChem 6 (1), pp. 95 - 103 (2005)

Buth, H.; Wolters, B.; Hartwig, B.; Meier-Bornheim, R.; Veith, H.; Hansen, M.; Sommerhoff, C. P.; Schaschke, N.; Machleidt, W.; Fusenig, N. E. et al.; Boukamp, P.; Brix, K.: HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. European Journal of Cell Biology 83 (11), pp. 781 - 795 (2004)

Stern, I.; Schaschke, N.; Moroder, L.; Turk, D.: Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. Biochemical Journal 381, pp. 511 - 517 (2004)

Giragossian, C.; Schaschke, N.; Moroder, L.; Mierke, D. F.: Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor. Biochemistry 43 (10), pp. 2724 - 2731 (2004)

Schaschke, N.: Miraziridine A: natures blueprint towards protease class-spanning inhibitors. Bioorganic & Medicinal Chemistry Letters 14 (4), pp. 855 - 857 (2004)

Gil-Parrado, S.; Assfalg-Machleidt, I.; Fiorino, F.; Deluca, D.; Pfeiler, D.; Schaschke, N.; Moroder, L.; Machleidt, W.: Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin. Biological Chemistry 384 (3), pp. 395 - 402 (2003)

Schaschke, N.; Gabrijelcic-Geiger, D.; Dominik, A.; Sommerhoff, C. P.: Immobilized bivalent inhibitors as tools for the affinity-based isolation of human mast cell tryptases. Biopolymers 71 (3), p. 397 - 397 (2003)

Balaji, K. N.; Schaschke, N.; Machleidt, W.; Catalfamo, M.; Henkart, P. A.: Surface cathepsin B protects cytotoxic lymphocytes from self- destruction after degranulation. Journal of Experimental Medicine 196 (4), pp. 493 - 503 (2002)

Schaschke, N.; Deluca, D.; Assfalg-Machleidt, I.; Höhneke, C.; Sommerhoff, C. P.; Machleidt, W.: Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C- terminal heptapeptide segment of penetratin. Biological Chemistry 383 (5), pp. 849 - 852 (2002)

Schaschke, N.; Dominik, A.; Matschiner, G.; Sommerhoff, C. P.: Bivalent inhibition of beta-tryptase: Distance scan of neighboring subunits by dibasic inhibitors. Bioorganic & Medicinal Chemistry Letters 12 (6), pp. 985 - 988 (2002)

Pfizer, J. M.; Assfalg-Machleidt, I.; Machleidt, W.; Moroder, L.; Schaschke, N.: Primed-site probing of papain-like cysteine proteases. In: Peptides 2004, pp. 668 - 669 (Eds. Flegel, M.; Fridkin, M.; Gilon, C.; Slaninova, J.). Kenes International, Geneva/Switzerland (2005)

Schaschke, N.: Miraziridine A - A Three-In-One Protease Inhibitor. In: Peptides 2002, pp. 610 - 611 (Eds. Benedetti, E.; Pedone, C.). Edizioni Ziino, Napoli (2003)

Moroder, L.; Musiol, H.-J.; Schaschke, N.; Chen, L.; Hargittai, B.; Barany, G.: Protection of the Thiol group. In: Synthesis of Peptides and Peptidomimetics, pp. 384 - 423. Georg Thieme Verlag, Stuttgart (2001)

Schaschke, N.; Alefelder, S.; Musiol, H.-J.; Moroder, L.: Miscellaneous coupling reagents. In: Synthesis of Peptides and Peptidomimetics, pp. 581 - 588. Georg Thieme Verlag, Stuttgart (2001)