Publications of S. Steinbacher

Stanitzek, S.; Augustin, M. A.; Huber, R.; Kupke, T.; Steinbacher, S.: Structural basis of CTP-dependent peptide bond formation in coenzyme A biosynthesis catalyzed by Escherichia coli PPC synthetase. Structure 12 (11), pp. 1977 - 1988 (2004)

Echt, S.; Bauer, S.; Steinbacher, S.; Huber, R.; Bacher, A.; Fischer, M.: Potential anti-infective targets in pathogenic yeasts: Structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans. Journal of Molecular Biology 341 (4), pp. 1085 - 1096 (2004)

Laupitz, R.; Hecht, S.; Amslinger, S.; Zepeck, F.; Kaiser, J.; Richter, G.; Schramek, N.; Steinbacher, S.; Huber, R.; Arigoni, D. et al.; Bacher, A.; Eisenreich, W.; Rohdich, F.: Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. European Journal of Biochemistry 271 (13), pp. 2658 - 2669 (2004)

Steinbacher, S.; Schiffmann, S.; Bacher, A.; Fischer, M.: Metal sites in 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with the substrate ribulose 5-phosphate. Acta Crystallographica Section D-Biological Crystallography 60, pp. 1338 - 1340 (2004)

Fritze, I. M.; Linden, L.; Freigang, J.; Auerbach, G.; Huber, R.; Steinbacher, S.: The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase. Plant Physiology 134 (4), pp. 1388 - 1400 (2004)

Steinbacher, S.; Schiffmann, S.; Richter, G.; Huber, R.; Bacher, A.; Fischer, M.: Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with divalent metal ions and the substrate ribulose 5-phosphate - Implications for the catalytic mechanism. Journal of Biological Chemistry 278 (43), pp. 42256 - 42265 (2003)

Blaesse, M.; Kupke, T.; Huber, R.; Steinbacher, S.: Structure of MrsD, an FAD-binding protein of the HFCD family. Acta Crystallographica Section D-Biological Crystallography 59, pp. 1414 - 1421 (2003)

Steinbacher, S.; Kaiser, J.; Gerhardt, S.; Eisenreich, W.; Huber, R.; Bacher, A.; Rohdich, F.: Crystal structure of the type II isopentenyl diphosphate: Dimethylallyl diphosphate isomerase from Bacillus subtilis. Journal of Molecular Biology 329 (5), pp. 973 - 982 (2003)

Steinbacher, S.; Kaiser, J.; Eisenreich, W.; Huber, R.; Bacher, A.; Rohdich, F.: Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC) - Implications for the catalytic mechanism and anti-malaria drug development. Journal of Biological Chemistry 278 (20), pp. 18401 - 18407 (2003)

Steinbacher, S.; Hernandez-Acosta, P.; Bieseler, B.; Blaesse, M.; Huber, R.; Culianez-Macia, F. A.; Kupke, T.: Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate. Journal of Molecular Biology 327 (1), pp. 193 - 202 (2003)

Bauer, S.; Kemter, K.; Bacher, A.; Huber, R.; Fischer, M.; Steinbacher, S.: Crystal structure of Schizosaccharomyces pombe riboflavin kinase reveals a novel ATP and riboflavin-binding fold. Journal of Molecular Biology 326 (5), pp. 1463 - 1473 (2003)

Fischer, M. J.; Schott, A. K.; Kemter, K.; Feicht, R.; Richter, G.; Illarionov, B.; Eisenreich, W.; Gerhardt, S.; Cushman, M.; Steinbacher, S. et al.; Huber, R.; Bacher, A.: Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by ¹⁹F NMR protein perturbation experiments. BMC Biochemistry 4 (1), 18, pp. [1] - [19] (2003)

Fischer, M.; Römisch, W.; Schiffmann, S.; Kelly, M.; Oschkinat, H.; Steinbacher, S.; Huber, R.; Eisenreich, W.; Richter, G.; Bacher, A.: Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii. Journal of Biological Chemistry 277 (44), pp. 41410 - 41416 (2002)

Gerhardt, S.; Schott, A. K.; Kairies, N.; Cushman, M.; Illarionov, B.; Eisenreich, W.; Bacher, A.; Huber, R.; Steinbacher, S.; Fischer, M.: Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8- ribityllumazine. Structure 10 (10), pp. 1371 - 1381 (2002)

Steinbacher, S.; Kaiser, J.; Wungsintaweekul, J.; Hecht, S.; Eisenreich, W.; Gerhardt, S.; Bacher, A.; Rohdich, F.: Structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids. Journal of Molecular Biology 316 (1), pp. 79 - 88 (2002)

Gerhardt, S.; Haase, I.; Steinbacher, S.; Kaiser, J. T.; Cushman, M.; Bacher, A.; Huber, R.; Fischer, M.: The structural basis of riboflavion binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase. Journal of Molecular Biology 318, pp. 1317 - 1329 (2002)