Publications of S. Gerhardt

Ramsperger, A.; Augustin, M.; Schott, A. K.; Gerhardt, S.; Krojer, T.; Eisenreich, W.; Illarionov, B.; Cushman, M.; Bacher, A.; Huber, R. et al.; Fischer, M.: Crystal structure of an archaeal pentameric riboflavin synthase in complex with a substrate analog inhibitor - Stereochemical implications. Journal of Biological Chemistry 281 (2), pp. 1224 - 1232 (2006)

Koch, M.; Breithaupt, C.; Gerhardt, S.; Weber, S.; Cushman, M.; Huber, R.; Bacher, A.; Fischer, M.: Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase. European Journal of Biochemistry 271 (15), pp. 3208 - 3214 (2004)

Gerhardt, S.; Echt, S.; Busch, M.; Freigang, J.; Auerbach, G.; Bader, G.; Martin, W. F.; Bacher, A.; Huber, R.; Fischer, M.: Structure and properties of an engineered transketolase from maize. Plant Physiology 132 (4), pp. 1941 - 1949 (2003)

Steinbacher, S.; Kaiser, J.; Gerhardt, S.; Eisenreich, W.; Huber, R.; Bacher, A.; Rohdich, F.: Crystal structure of the type II isopentenyl diphosphate: Dimethylallyl diphosphate isomerase from Bacillus subtilis. Journal of Molecular Biology 329 (5), pp. 973 - 982 (2003)

Fischer, M. J.; Schott, A. K.; Kemter, K.; Feicht, R.; Richter, G.; Illarionov, B.; Eisenreich, W.; Gerhardt, S.; Cushman, M.; Steinbacher, S. et al.; Huber, R.; Bacher, A.: Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by ¹⁹F NMR protein perturbation experiments. BMC Biochemistry 4 (1), 18, pp. [1] - [19] (2003)

Cushman, M.; Yang, D. L.; Mihalic, J. T.; Chen, J. H.; Gerhardt, S.; Huber, R.; Fischer, M.; Kis, K.; Bacher, A.: Incorporation of an amide into 5-phosphonoalkyl-6-D- ribitylaminopyrimidinedione lumazine synthase inhibitors results in an unexpected reversal of selectivity for riboflavin synthase vs lumazine synthase. Journal of Organic Chemistry 67 (20), pp. 6871 - 6877 (2002)

Gerhardt, S.; Schott, A. K.; Kairies, N.; Cushman, M.; Illarionov, B.; Eisenreich, W.; Bacher, A.; Huber, R.; Steinbacher, S.; Fischer, M.: Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8- ribityllumazine. Structure 10 (10), pp. 1371 - 1381 (2002)

Cushman, M.; Yang, D. L.; Gerhardt, S.; Huber, R.; Fischer, M.; Kis, K.; Bacher, A.: Design, synthesis, and evaluation of 6-carboxyalkyl and 6- phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase. Journal of Organic Chemistry 67 (16), pp. 5807 - 5816 (2002)

Steinbacher, S.; Kaiser, J.; Wungsintaweekul, J.; Hecht, S.; Eisenreich, W.; Gerhardt, S.; Bacher, A.; Rohdich, F.: Structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids. Journal of Molecular Biology 316 (1), pp. 79 - 88 (2002)

Fischer, M.; Haase, I.; Feicht, R.; Richter, G.; Gerhardt, S.; Changeux, J. P.; Huber, R.; Bacher, A.: Biosynthesis of riboflavin - 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. European Journal of Biochemistry 269 (2), pp. 519 - 526 (2002)

Gerhardt, S.; Haase, I.; Steinbacher, S.; Kaiser, J. T.; Cushman, M.; Bacher, A.; Huber, R.; Fischer, M.: The structural basis of riboflavion binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase. Journal of Molecular Biology 318, pp. 1317 - 1329 (2002)