Publications of Ruben Fernandez-Busnadiego

Saha, I.; Yuste-Checa, P.; Padilha, M. D. S.; Guo, Q.; Körner, R.; Holthusen, H.; Trinkaus, V. A.; Dudanova, I.; Fernandez-Busnadiego, R.; Baumeister, W. et al.; Sanders, D. W.; Gautam, S.; Diamond, M. I.; Hartl, F. U.; Hipp, M. S.: The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system. Nature Communications 14 (1), 560 (2023)

Riemenschneider, H.; Guo, Q.; Bader, J. M.; Frottin, F.; Farny, D.; Kleinberger, G.; Haass, C.; Mann, M.; Hartl, F. U.; Baumeister, W. et al.; Hipp, M. S.; Meissner, F.; Fernandez-Busnadiego, R.; Edbauer, D.: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. EMBO Reports 23 (6), e53890 (2022)

Riera Tur, I.; Schäfer, T.; Hornburg, D.; Mishra, A.; da Silva Padilha, M.; Fernandez-Mosquera, L.; Feigenbutz, D.; Auer, P.; Mann, M.; Baumeister, W. et al.; Klein, R.; Meissner, F.; Raimundo, N.; Fernandez-Busnadiego, R.; Dudanova, I.: Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity. Life science alliance 5 (3), e202101185 (2022)

Huang, B.; Guo, Q.; Niedermeier, M. L.; Cheng, J.; Engler, T.; Maurer, M.; Pautsch, A.; Baumeister, W.; Stengel, F.; Kochanek, S. et al.; Fernandez-Busnadiego, R.: Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex. Structure 29 (8), pp. 804 - 809 (2021)

Trinkaus, V. A.; Riera-Tur, I.; Martinez Sanchez, A.; Bäuerlein, F. J. B.; Guo, Q.; Arzberger, T.; Baumeister, W.; Dudanova, I.; Hipp, M. S.; Hartl, F. U. et al.; Fernandez-Busnadiego, R.: In situ architecture of neuronal alpha-Synuclein inclusions. Nature Communications 12 (1), 2110 (2021)

Bäuerlein, F. J. B.; Fernandez-Busnadiego, R.; Baumeister, W.: Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells. Trends in Cell Biology 30 (12), pp. 951 - 966 (2020)

Salfer, M.; Collado, J. F.; Baumeister, W.; Fernandez-Busnadiego, R.; Martinez-Sanchez, A.: Reliable estimation of membrane curvature for cryo-electron tomography. PLoS Computational Biology 16 (8), e1007962 (2020)

Yasuda, S.; Tsuchiya, H.; Kaiho, A.; Guo, Q.; Ikeuchi, K.; Endo, A.; Arai, N.; Ohtake, F.; Murata, S.; Inada, T. et al.; Baumeister, W.; Fernandez-Busnadiego, R.; Tanaka, K.; Saeki, Y.: Stress- and ubiquitylation-dependent phase separation of the proteasome. NATURE 578, pp. 296 - 300 (2020)

Seefelder, M.; Alva, V.; Huang, B.; Engler, T.; Baumeister, W.; Guo, Q.; Fernandez-Busnadiego, R.; Lupas, A. N.; Kochanek, S.: The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin. BMC Evolutionary Biology 20, 162 (2020)

Chen, Y.; Yong, J.; Martinez Sanchez, A.; Yang, Y.; Wu, Y.; De Camilli, P.; Fernandez-Busnadiego, R.; Wu, M.: Dynamic instability of clathrin assembly provides proofreading control for endocytosis. JOURNAL OF CELL BIOLOGY 218 (10), pp. 3200 - 3211 (2019)

Collado, J.; Kalemanov, M.; Campelo, F.; Bourgoint, C.; Thomas, F.; Loewith, R.; Martinez Sanchez, A.; Baumeister, W.; Stefan, C. J.; Fernandez-Busnadiego, R.: Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity. DEVELOPMENTAL CELL 51 (4), pp. 476 - 487.e7 (2019)

Guo, Q.; Huang, B.; Cheng, J.; Seefelder, M.; Engler, T.; Pfeifer, G.; Oeckl, P.; Otto, M.; Moser, F.; Maurer, M. et al.; Pautsch, A.; Baumeister, W.; Fernandez-Busnadiego, R.; Kochanek, S.: The cryo-electron microscopy structure of huntingtin. Nature 555 (7694), pp. 117 - 120 (2018)

Gruber, A.; Hornburg, D.; Antonin, M.; Krahmer, N.; Collado, J.; Schaffer, M.; Zubaite, G.; Luechtenborg, C.; Sachsenheimer, T.; Bruegger, B. et al.; Mann, M.; Baumeister, W.; Hartl, F. U.; Hipp, M. S.; Fernandez-Busnadiego, R.: Molecular and structural architecture of polyQ aggregates in yeast. Proceedings of the National Academy of Sciences of the United States of America 115 (15), pp. E3446 - E3453 (2018)

Guo, Q.; Lehmer, C.; Martinez Sanchez, A.; Rudack, T.; Beck, F.; Hartmann, H.; Perez-Berlanga, M.; Frottin, F.; Hipp, M. S.; Hartl, F. U. et al.; Edbauer, D.; Baumeister, W.; Fernandez-Busnadiego, R.: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell 172 (4), pp. 696 - 705.e12 (2018)

Bäuerlein, F. J. B.; Saha, I.; Mishra, A.; Kalemanov, M.; Martinez-Sanchez, A.; Klein, R.; Dudanova, I.; Hipp, M. S.; Hartl, F. U.; Baumeister, W. et al.; Fernandez-Busnadiego, R.: In Situ Architecture and Cellular Interactions of PolyQ Inclusions. Cell 171 (1), e10, pp. 179 - 187.e10 (2017)

Collado, J.; Fernandez-Busnadiego, R.: Deciphering the molecular architecture of membrane contact sites by cryo-electron tomography. SI 1864 (9), pp. 1507 - 1512 (2017)

Wagner, J.; Schaffer, M.; Fernandez-Busnadiego, R.: Cryo-electron tomography-the cell biology that came in from the cold. FEBS Letters 591 (17), pp. 2520 - 2533 (2017)

Lucic, V.; Fernandez-Busnadiego, R.; Laugks, U.; Baumeister, W.: Hierarchical detection and analysis of macromolecular complexes in cryo-electron tomograms using Pyto software. Journal of Structural Biology 196 (3), pp. 503 - 514 (2016)

Nagy, I.; Knispel, R. W.; Kofler, C.; Orsini, M.; Boicu, M.; Varga, S.; Weyher-Stingl, E.; Sun, N.; Fernandez-Busnadiego, R.; Kukolya, J. et al.; Nickell, S.; Baumeister, W.: Lipoprotein-like particles in a prokaryote: quinone droplets of Thermoplasma acidophilum. FEMS Microbiology Letters 363 (18), fnw169 (2016)

Fernandez-Busnadiego, R.: Supramolecular architecture of endoplasmic reticulum - plasma membrane contact sites. Biochemical Society Transactions (London) 44, pp. 534 - 540 (2016)