Publications of Barbara Steigenberger

Sperk, A.; Gabriel, A.; Koch, D.; Augsburger, A.; Sanchez, V.; Brockelt, D.; Oellinger, R.; Engleitner, T.; Giansanti, P.; Ludwig, R. et al.; Der Maur, P. A.; Walter, W.; Haferlach, T.; Jeremias, I.; Rad, R.; Steigenberger, B.; Kuster, B.; Eichner, R.; Bassermann, F.: FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells. Leukemia 38 (9), pp. 2027 - 2031 (2024)

Horn-Ghetko, D.; Hopf, L. V. M.; Tripathi-Giesgen, I.; Du, J.; Kostrhon, S.; Tung Vu, D.; Beier, V.; Steigenberger, B.; Prabu, J. R.; Stier, L. et al.; Bruss, E. M.; Mann, M.; Xiong, Y.; Schulman, B. A.: Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature Structural & Molecular Biology 31 (7), pp. 1083 - 1094 (2024)

Tölke, A. J.; Gaisbauer, J. F.; Gärtner, Y. V.; Steigenberger, B.; Holovan, A.; Streshnev, F.; Schneider, S.; Müller, M.; Carell, T.: Efficient Tandem Copper‐Catalyzed Click Synthesis of Multisugar‐Modified Oligonucleotides. Angewandte Chemie International Edition 63 (25), e202405161 (2024)

Liu, X.; Novak, B.; Namendorf, C.; Steigenberger, B.; Zhang, Y.; Turck, C. W.: Long-lived proteins and DNA as candidate predictive biomarkers for tissue associated diseases. iScience 27 (4), 109642 (2024)

Li, J.; Purser, N.; Liwocha, J.; Scott, D. C.; Byers, H. A.; Steigenberger, B.; Hill, S.; Tripathi-Giesgen, I.; Hinkle, T.; Hansen, F. M. et al.; Prabu, J. R.; Radhakrishnan, S. K.; Kirkpatrick, D. S.; Reichermeier, K. M.; Schulman, B. A.; Kleiger, G.: Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting. Molecular Cell 84 (7), pp. 1304 - 1320 (2024)

Galanti, L.; Peritore, M.; Gnugge, R.; Cannavo, E.; Heipke, J.; Palumbieri, M. D.; Steigenberger, B.; Symington, L. S.; Cejka, P.; Pfander, B.: Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination. Nature Communications 15 (1), 2890 (2024)

Liwocha, J.; Li, J.; Purser, N.; Rattanasopa, C.; Maiwald, S.; Krist, D. T.; Scott, D. C.; Steigenberger, B.; Prabu, J. R.; Schulman, B. A. et al.; Kleiger, G.: Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature Structural & Molecular Biology 31 (2), pp. 378 - 389 (2024)

Pichler, A.; Hillmeier, M.; Heiss, M.; Peev, E.; Xefteris, S.; Steigenberger, B.; Thoma, I.; Mueller, M.; Borso, M.; Imhof, A. et al.; Carell, T.: Synthesis and Structure Elucidation of Glutamyl-Queuosine. The Journal of Organic Chemistry 145 (47), pp. 25528 - 25532 (2023)

Kolb, J.; Tsata, V.; John, N.; Kim, K.; Mockel, C.; Rosso, G.; Kurbel, V.; Parmar, A.; Sharma, G.; Karandasheva, K. et al.; Abuhattum, S.; Lyraki, O.; Beck, T.; Mueller, P.; Schluessler, R.; Frischknecht, R.; Wehner, A.; Krombholz, N.; Steigenberger, B.; Beis, D.; Takeoka, A.; Bluemcke, I.; Moellmert, S.; Singh, K.; Guck, J.; Kobow, K.; Wehner, D.: Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment. Nature Communications 14 (1), 6814 (2023)

Bonneau, F.; Basquin, J.; Steigenberger, B.; Schäfer, T.; Schäfer, I. B.; Conti, E.: Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA–RNA interactions. Genes & Development 37 (11-12), pp. 505 - 517 (2023)

Rotheneeder, M.; Stakyte, K.; van de Logt, E.; Bartho, J. D.; Lammens, K.; Fan, Y.; Alt, A.; Kessler, B.; Jung, C.; Roos, W. P. et al.; Steigenberger, B.; Hopfner, K.-P.: Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Molecular Cell 83 (2), pp. 167 - 185 (2023)

Qiao, S.; Lee, C.-W.; Sherpa, D.; Chrustowicz, J.; Cheng, J. D.; Duennebacke, M.; Steigenberger, B.; Karayel, O.; Tung Vu, D.; Gronau, S. v. et al.; Mann, M.; Wilfling, F.; Schulman, B.: Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature Communications 13 (1), 3041 (2022)

Taschner, M.; Basquin, J.; Steigenberger, B.; Schäfer, I. B.; Soh, Y.-M.; Basquin, C.; Lorentzen, E.; Raeschle, M.; Scheltema, R. A.; Gruber, S.: Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding. EMBO Journal 40, e107807 (2021)