Publications of F. U. Hartl

Shomura, Y.; Dragovic, Z.; Chang, H. C.; Tzvetkov, N.; Young, J. C.; Brodsky, J. L.; Guerriero, V.; Hartl, F. U.; Bracher, A.: Regulation of Hsp70 function by HspBP1: Structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange. Molecular Cell 17 (3), pp. 367 - 379 (2005)

Young, J. C.; Agashe, V. R.; Siegers, K.; Hartl, F. U.: Pathways of chaperone-mediated protein folding in the cytosol. Nature Reviews Molecular Cell Biology 5 (10), pp. 781 - 791 (2004)

Hartl, U.: Role of molecular chaperones in de novo protein folding and in misfolding disease. Protein Science 13 (Suppl. Suppl. 1), p. 67 - 67 (2004)

Schaffar, G.; Breuer, P.; Boteva, R.; Behrends, C.; Tzvetkov, N.; Strippel, N.; Sakahira, H.; Siegers, K.; Hayer-Hartl, M.; Hartl, F. U.: Cellular toxicity of polyglutamine expansion proteins: Mechanism of transcription factor deactivation. Molecular Cell 15 (1), pp. 95 - 105 (2004)

Etchells, S. A.; Hartl, F. U.: The dynamic tunnel. Nature Structural & Molecular Biology 11 (5), pp. 391 - 392 (2004)

Agashe, V. R.; Guha, S.; Chang, H. C.; Genevaux, P.; Hayer-Hartl, M.; Stemp, M.; Georgopoulos, C.; Hartl, F. U.; Barral, J. M.: Function of trigger factor and DnaK in multidomain protein folding: Increase in yield at the expense of folding speed. Cell 117 (2), pp. 199 - 209 (2004)

Wochnik, G. M.; Young, J. C.; Schmidt, U.; Holsboer, F.; Hartl, F. U.; Rein, T.: Inhibition of GR-mediated transcription by p23 requires interaction with Hsp90. FEBS Letters 560 (1-3), pp. 35 - 38 (2004)

Barral, J. M.; Broadley, S. A.; Schaffar, G.; Hartl, F. U.: Roles of molecular chaperones in protein misfolding diseases. Seminars in Cell & Developmental Biology 15 (1), pp. 17 - 29 (2004)

Genevaux, P.; Keppel, F.; Schwager, F.; Langendijk-Genevaux, P. S.; Hartl, F. U.; Georgopoulos, C.: In vivo analysis of the overlapping functions of DnaK and trigger factor. EMBO Reports 5 (2), pp. 195 - 200 (2004)

Figueiredo, L.; Klunker, D.; Ang, D.; Naylor, D. J.; Kerner, M. J.; Georgopoulos, C.; Hartl, F. U.; Hayer-Hartl, M.: Functional characterization of an archaeal GroEL/GroES chaperonin system - Significance of substrate encapsulation. Journal of Biological Chemistry 279 (2), pp. 1090 - 1099 (2004)

Hartl, F. U.: Molecular chaperone action in polyglutamine aggregation disease. Biophysical Journal 86 (1), p. 166A - 166A (2004)

Rosenhagen, M. C.; Soti, C.; Schmidt, U.; Wochnik, G. M.; Hartl, F. U.; Holsboer, F.; Young, J. C.; Rein, T.: The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation. Molecular Endocrinology 17 (10), pp. 1991 - 2001 (2003)

Siegers, K.; Bolter, B.; Schwarz, J. P.; Böttcher, U. M. K.; Guha, S.; Hartl, F. U.: TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes. EMBO Journal 22 (19), pp. 5230 - 5240 (2003)

Young, J. C.; Barral, J. M.; Hartl, F. U.: More than folding: localized functions of cytosolic chaperones. Trends in Biochemical Sciences 28 (10), pp. 541 - 547 (2003)

Klunker, D.; Haas, B.; Hirtreiter, A.; Figueiredo, L.; Naylor, D. J.; Pfeifer, G.; Muller, V.; Deppenmeier, U.; Gottschalk, G.; Hartl, F. U. et al.; Hayer-Hartl, M.: Coexistence of group I and group II chaperonins in the archaeon Methanosarcina mazei. Journal of Biological Chemistry 278 (35), pp. 33256 - 33267 (2003)

Brychzy, A.; Rein, T.; Winklhofer, K. F.; Hartl, F. U.; Young, J. C.; Obermann, W. M. J.: Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system. EMBO Journal 22 (14), pp. 3613 - 3623 (2003)

Young, J. C.; Hartl, F. U.: A stress sensor for the bacterial periplasm. Cell 113 (1), pp. 1 - 2 (2003)

Hartl, F. U.: Chaperone-assisted protein folding in the cytosol. FASEB Journal 17 (4 Suppl. S), p. A559 - A559 (2003)

Schmidt, U.; Wochnik, G. M.; Rosenhagen, M. C.; Young, J. C.; Hartl, F. U.; Holsboer, F.; Rein, T.: Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor. Journal of Biological Chemistry 278 (7), pp. 4926 - 4931 (2003)

Dou, F.; Netzer, W. J.; Tanemura, K.; Li, F.; Hartl, F. U.; Takashima, A.; Gouras, G. K.; Greengard, P.; Xu, H. X.: Chaperones increase association of tau protein with microtubules. Proceedings of the National Academy of Sciences of the United States of America 100 (2), pp. 721 - 726 (2003)