Publications of P. Breuer

Breuer, P.; Haacke, A.; Evert, B. O.; Wullner, U.: Nuclear Aggregation of Polyglutamine-expanded Ataxin-3 FRAGMENTS ESCAPE THE CYTOPLASMIC QUALITY CONTROL. Journal of Biological Chemistry 285 (9), pp. 6532 - 6537 (2010)

Haacke, A.; Hartl, F. U.; Breuer, P.: Calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3. JOURNAL OF BIOLOGICAL CHEMISTRY 282 (26), pp. 18851 - 18856 (2007)

Boeddrich, A.; Gaumer, B.; Haacke, A.; Tzvetkov, N.; Albrecht, M.; Evert, B. O.; Muller, E. C.; Lurz, R.; Breuer, P.; Schugardt, N. et al.; Plassmann, S.; Xu, K. X.; Warrick, J. M.; Suopanki, J.; Wullner, U.; Frank, R.; Hartl, F. U.; Bonini, N. M.; Wanker, E. E.: An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO Journal 25 (7), pp. 1547 - 1558 (2006)

Haacke, A.; Broadley, S. A.; Boteva, R.; Tzvetkov, N.; Hartl, F. U.; Breuer, P.: Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3. Human Molecular Genetics 15 (4), pp. 555 - 568 (2006)

Tzvetkov, N.; Breuer, P.; Boteva, R.: Cysteine-free glutathione-S-tranferase as a tool for thiol-specific labeling of proteins. BioTechniques 40 (2), pp. 145 - 146 (2006)

Schaffar, G.; Breuer, P.; Boteva, R.; Behrends, C.; Tzvetkov, N.; Strippel, N.; Sakahira, H.; Siegers, K.; Hayer-Hartl, M.; Hartl, F. U.: Cellular toxicity of polyglutamine expansion proteins: Mechanism of transcription factor deactivation. Molecular Cell 15 (1), pp. 95 - 105 (2004)

Sakahira, H.; Breuer, P.; Hayer-Hartl, M. K.; Hartl, F. U.: Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America 99 (Suppl. 4), pp. 16412 - 16418 (2002)