Publications of Kyle R. Legate

Shi, Y.; Berking, A.; Baade, T.; Legate, K. R.; Fässler, R.; Hauck, C. R.: PIP5KI gamma 90-generated phosphatidylinositol-4,5-bisphosphate promotes the uptake of Staphylococcus aureus by host cells. Molecular Microbiology 116, pp. 1249 - 1267 (2021)

Winograd-Katz, S. E.; Fässler, R.; Geiger, B.; Legate, K. R.: The integrin adhesome: from genes and proteins to human disease. NATURE REVIEWS MOLECULAR CELL BIOLOGY 15 (4), pp. 273 - 288 (2014)

Legate, K. R.; Montag, D.; Böttcher, R. T.; Takahashi, S.; Fässler, R.: Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type I gamma in vivo. JOURNAL OF CELL SCIENCE 125 (23), pp. 5636 - 5646 (2012)

Azimifar, S. B.; Böttcher, R. T.; Zanivan, S.; Grashoff, C.; Krüger, M.; Legate, K. R.; Mann, M.; Fässler, R.: Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor. Journal of Cell Science 125 (2), pp. 435 - 448 (2012)

Legate, K. R.; Takahashi, S.; Bonakdar, N.; Fabry, B.; Boettiger, D.; Zent, R.; Fässler, R.: Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)(2) synthesis. EMBO Journal 30 (22), pp. 4539 - 4553 (2011)

Legate, K. R.: A novel role for PtdIns(4,5)P-2 in force coupling integrins to the cytoskeleton. Biochemistry and Cell Biology-Biochimie et Biologie Cellulaire 89 (2), p. 263 - 263 (2011)

Wernimont, S. A.; Legate, K. R.; Simonson, W. T. N.; Fässler, R.; Huttenlocher, A.: PIPKI gamma 90 Negatively Regulates LFA-1-Mediated Adhesion and Activation in Antigen-Induced CD4(+) T Cells. Journal of Immunology 185 (8), pp. 4714 - 4723 (2010)

Legate, K. R.; Boettiger, D.; Faessler, R.: Deleting PIP kinase type I gamma from focal adhesions reduces integrin bond tension without affecting the ability of integrins to bind ligand. European Journal of Cell Biology 89 (Suppl. 60), p. 50 - 50 (2010)

Moser, M.; Legate, K. R.; Zent, R.; Fässler, R.: The Tail of Integrins, Talin, and Kindlins. Science 324 (5929), pp. 895 - 899 (2009)

Legate, K. R.; Barocke, V.; Massberg, S.; Fässler, R.: Local production of phosphoinositides enhances cellular adhesion strength by accelerating talin recruitment to nascent focal adhesions. European Journal of Cell Biology 88 (Suppl. Suppl. 59), p. 75 - 75 (2009)

Legate, K. R.; Wickström, S. A.; Fässler, R.: Genetic and cell biological analysis of integrin outside-in signaling. Genes & Development 23 (4), pp. 397 - 418 (2009)

Legate, K. R.; Fässler, R.: Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails. Journal of Cell Science 122 (2), pp. 187 - 198 (2009)

Czuchra, A.; Meyer, H.; Legate, K. R.; Brakebusch, C.; Fässler, R.: Genetic analysis of β1 integrin "activation motifs" in mice. Journal of Cell Biology 174 (6), pp. 889 - 899 (2006)

Aszodi, A.; Legate, K. R.; Nakchbandi, I.; Fässler, R.: What mouse mutants teach us about extracellular matrix function. Ann. Rev. Cell Dev. Biol. 22, pp. 591 - 621 (2006)

Legate, K. R.; Montanez, E.; Kudlacek, O.; Fässler, R.: ILK, PINCH and parvin: the tIPP of integrin signalling. Nature Reviews Molecular Cell Biology 7 (1), pp. 20 - 31 (2006)

Wiesner, S.; Legate, K. R.; Fässler, R.: Integrin-actin interactions. CMLS-Cellular and Molecular Life Sciences 62 (10), pp. 1081 - 1099 (2005)