Publications of Carsten Grashoff

Fischer, L.; Klingner, C.; Schlichthärle, T.; Strauss, M. T.; Böttcher, R. T.; Fässler, R.; Jungmann, R.; Grashoff, C.: Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion. Nature Communications 12 (1), 919 (2021)

Kanoldt, V.; Kluger, C.; Barz, C.; Schweizer, A.-L.; Ramanujam, D.; Windgasse, L.; Engelhardt, S.; Chrostek-Grashoff, A.; Grashoff, C.: Metavinculin modulates force transduction in cell adhesion sites. Nature Communications 11 (1), 6403 (2020)

Cost, A.-L.; Khalaji, S.; Grashoff, C.: Genetically Encoded FRET-Based Tension Sensors. Current Protocols in Cell Biology 83 (1), e85 (2019)

Lemke, S. B.; Weidemann, T.; Cost, A.-L.; Grashoff, C.; Schnorrer, F.: A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo. PLoS Biology 17 (3), e3000057 (2019)

Kanoldt, V.; Fischer, L.; Grashoff, C.: Unforgettable force - crosstalk and memory of mechanosensitive structures. Biological Chemistry, pp. 687 - 698 (2018)

Price, A. J.; Cost, A.-L.; Ungewiss, H.; Waschke, J.; Dunn, A. R.; Grashoff, C.: Mechanical loading of desmosomes depends on the magnitude and orientation of external stress. Nature Communications 9, 5284 (2018)

Ringer, P.; Colo, G.; Fässler, R.; Grashoff, C.: Sensing the mechano-chemical properties of the extracellular matrix. Matrix Biology 64, pp. 6 - 16 (2017)

Freikamp, A.; Mehlich, A.; Klingner, C.; Grashoff, C.: Investigating piconewton forces in cells by FRET-based molecular force microscopy. SI 197 (1), pp. 37 - 42 (2017)

Ringer, P.; Weissl, A.; Cost, A.-L.; Freikamp, A.; Sabass, B.; Mehlich, A.; Tramier, M.; Rief, M.; Grashoff, C.: Multiplexing molecular tension sensors reveals piconewton force gradient across talin-1. Nature methods 14 (11), pp. 1090 - 1096 (2017)

Freikamp, A.; Cost, A.-L.; Grashoff, C.: The Piconewton Force Awakens: Quantifying Mechanics in Cells. Trends in Cell Biology 26 (11), pp. 838 - 847 (2016)

Cost, A.-L.; Ringer, P.; Chrostek-Grashoff, A.; Grashoff, C.: How to Measure Molecular Forces in Cells: A Guide to Evaluating Genetically-Encoded FRET-Based Tension Sensors. Cellular and Molecular Bioengineering 8 (1), pp. 96 - 105 (2015)

Austen, K.; Ringer, P.; Mehlich, A.; Chrostek-Grashoff, A.; Kluger, C.; Klingner, C.; Sabass, B.; Zent, R.; Rief, M.; Grashoff, C.: Extracellular rigidity sensing by talin isoform-specific mechanical linkages. NATURE CELL BIOLOGY 17 (12), pp. 1597 - 1606 (2015)

Leerberg, J. M.; Gomez, G. A.; Verma, S.; Moussa, E. J.; Wu, S. K.; Priya, R.; Hoffman, B. D.; Grashoff, C.; Schwartz, M. A.; Yap, A. S.: Tension-Sensitive Actin Assembly Supports Contractility at the Epithelial Zonula Adherens. CURRENT BIOLOGY 24 (15), pp. 1689 - 1699 (2014)

Elad, N.; Volberg, T.; Patla, I.; Hirschfeld-Warneken, V.; Grashoff, C.; Spatz, J. P.; Fässler, R.; Geiger, B.; Medalia, O.: The role of integrin-linked kinase in the molecular architecture of focal adhesions. JOURNAL OF CELL SCIENCE 126 (18), pp. 4099 - 4107 (2013)

Kayser, J.; Haslbeck, M.; Dempfle, L.; Krause, M.; Grashoff, C.; Buchner, J.; Herrmann, H.; Bausch, A. R.: The Small Heat Shock Protein Hsp27 Affects Assembly Dynamics and Structure of Keratin Intermediate Filament Networks. BIOPHYSICAL JOURNAL 105 (8), pp. 1778 - 1785 (2013)

Moik, D.; Böttcher, A.; Makhina, T.; Grashoff, C.; Bulus, N.; Zent, R.; Fässler, R.: Mutations in the Paxillin-binding Site of Integrin-linked Kinase (ILK) Destabilize the Pseudokinase Domain and Cause Embryonic Lethality in Mice. JOURNAL OF BIOLOGICAL CHEMISTRY 288 (26), pp. 18863 - 18871 (2013)

Azimifar, S. B.; Böttcher, R. T.; Zanivan, S.; Grashoff, C.; Krüger, M.; Legate, K. R.; Mann, M.; Fässler, R.: Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor. Journal of Cell Science 125 (2), pp. 435 - 448 (2012)

Patla, I.; Volberg, T.; Elad, N.; Hirschfeld-Warneken, V.; Grashoff, C.; Fässler, R.; Spatz, J. P.; Geiger, B.; Medalia, O.: Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography. Nature Cell Biology 12 (9), pp. 909 - 915 (2010)

Stanchi, F.; Grashoff, C.; Yonga, C. F. N.; Grall, D.; Fässler, R.; Van Obberghen-Schilling, E.: Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation. Journal of Cell Science 122 (11), pp. 1800 - 1811 (2009)

Bergmann, S.; Lang, A.; Rohde, M.; Agarwal, V.; Rennemeier, C.; Grashoff, C.; Preissner, K. T.; Hammerschmidt, S.: Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells. Journal of Cell Science 122 (2), pp. 256 - 267 (2009)