Publications of F. U. Hartl

Stotz, M.; Mueller-Cajar, O.; Ciniawsky, S.; Wendler, P.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Structure of green-type Rubisco activase from tobacco. Nature Structural & Molecular Biology 18 (12), pp. 1366 - 1370 (2011)

Mueller-Cajar, O.; Stotz, M.; Wendler, P.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Structure and function of the AAA(+) protein CbbX, a red-type Rubisco activase. Nature 479 (7372), pp. 194 - 199 (2011)

Gupta, R.; Kasturi, P.; Bracher, A.; Loew, C.; Zheng, M.; Villella, A.; Garza, D.; Hartl, F. U.; Raychaudhuri, S.: Firefly luciferase mutants as sensors of proteome stress. Nature Methods 8 (10), pp. 879 - 886 (2011)

Hartl, F. U.: Chaperone-assisted protein folding: the path to discovery from a personal perspective. Nature Medicine 17 (10), pp. 1206 - 1210 (2011)

Bracher, A.; Starling-Windhof, A.; Hartl, F. U.; Hayer-Hartl, M.: Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco. Nature Structural & Molecular Biology 18 (8), pp. 875 - 880 (2011)

Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Molecular chaperones in protein folding and proteostasis. Nature 475 (7356), pp. 324 - 332 (2011)

Resenberger, U. K.; Harmeier, A.; Woerner, A. C.; Goodman, J. L.; Müller, V.; Krishnan, R.; Vabulas, R. M.; Kretzschmar, H. A.; Lindquist, S.; Hartl, F. U. et al.; Multhaup, G.; Winklhofer, K. F.; Tatzelt, J.: The cellular prion protein mediates neurotoxic signalling of beta-sheet-rich conformers independent of prion replication. EMBO Journal 30 (10), pp. 2057 - 2070 (2011)

Vabulas, R. M.; Hartl, F. U.: Aberrant protein interactions in amyloid disease. Cell Cycle 10 (10), pp. 1512 - 1513 (2011)

Olzscha, H.; Schermann, S. M.; Woerner, A. C.; Pinkert, S.; Hecht, M. H.; Tartaglia, G. G.; Vendruscolo, M.; Hayer-Hartl, M.; Hartl, F. U.; Vabulas, R. M.: Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions. Cell 144 (1), pp. 67 - 78 (2011)

Vabulas, R. M.; Raychaudhuri, S.; Hayer-Hartl, M.; Hartl, F. U.: Protein Folding in the Cytoplasm and the Heat Shock Response. Cold Spring Harbor Perspectives in Biology 2 (12), a004390, pp. [1] - [18] (2010)

Lakshmipathy, S. K.; Gupta, R.; Pinkert, S.; Etchells, S. A.; Hartl, F. U.: Versatility of Trigger Factor Interactions with Ribosome-Nascent Chain Complexes. Journal of Biological Chemistry 285 (36), pp. 27911 - 27923 (2010)

Polier, S.; Hartl, F. U.; Bracher, A.: Interaction of the Hsp110 Molecular Chaperones from S. cerevisiae with Substrate Protein. Journal of Molecular Biology 401 (5), pp. 696 - 707 (2010)

Brandt, F.; Carlson, L. A.; Hartl, F. U.; Baumeister, W.; Grünewald, K.: The Three-Dimensional Organization of Polyribosomes in Intact Human Cells. Molecular Cell 39 (4), pp. 560 - 569 (2010)

Ortiz, J. O.; Brandt, F.; Matias, V. R. F.; Sennels, L.; Rappsilber, J.; Scheres, S. H. W.; Eibauer, M.; Hartl, F. U.; Baumeister, W.: Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ. Journal of Cell Biology 190 (4), pp. 613 - 621 (2010)

Gupta, R.; Lakshmipathy, S. K.; Chang, H. C.; Etchells, S. A.; Hartl, F. U.: Trigger factor lacking the PPIase domain can enhance the folding of eukaryotic multi-domain proteins in Escherichia coli. FEBS Letters 584 (16), pp. 3620 - 3624 (2010)

Tartaglia, G. G.; Dobson, C. M.; Hartl, F. U.; Vendruscolo, M.: Physicochemical Determinants of Chaperone Requirements. Journal of Molecular Biology 400 (3), pp. 579 - 588 (2010)

Chakraborty, K.; Chatila, M.; Sinha, J.; Shi, Q. Y.; Poschner, B. C.; Sikor, M.; Jiang, G. X.; Lamb, D. C.; Hartl, F. U.; Hayer-Hartl, M.: Chaperonin-Catalyzed Rescue of Kinetically Trapped States in Protein Folding. Cell 142 (1), pp. 112 - 122 (2010)

Liu, C. M.; Young, A. L.; Starling-Windhof, A.; Bracher, A.; Saschenbrecker, S.; Rao, B. V.; Rao, K. V.; Berninghausen, O.; Mielke, T.; Hartl, F. U. et al.; Beckmann, R.; Hayer-Hartl, M.: Coupled chaperone action in folding and assembly of hexadecameric Rubisco. Nature 463 (7278), pp. 197 - 202 (2010)

Hirtreiter, A. M.; Calloni, G.; Forner, F.; Scheibe, B.; Puype, M.; Vandekerckhove, J.; Mann, M.; Hartl, F. U.; Hayer-Hartl, M.: Differential substrate specificity of group I and group II chaperonins in the archaeon Methanosarcina mazei. Molecular Microbiology 74 (5), pp. 1152 - 1168 (2009)

Broadley, S. A.; Hartl, F. U.: The role of molecular chaperones in human misfolding diseases. FEBS Letters 583 (16), pp. 2647 - 2653 (2009)