
Publications of F. Ulrich Hartl
All genres
Journal Article (194)
1.
Journal Article
: Regulated Proteolysis Induces Aberrant Phase Transition of Biomolecular Condensates into Aggregates: A Protective Role for the Chaperone Clusterin. Journal of Molecular Biology 436 (23), 168839 (2024)
2.
Journal Article
31 (12), pp. 1888 - 1897 (2024)
Resolving chaperone-assisted protein folding on the ribosome at the peptide level. Nature Structural & Molecular Biology 3.
Journal Article
633 (8029), pp. 459 - 464 (2024)
Visualizing chaperonin function in situ by cryo-electron tomography. Nature 4.
Journal Article
: Single-molecule digital sizing of proteins in solution. Nature Communications 15 (1), 7740 (2024)
5.
Journal Article
187 (17), pp. 4656 - 4673.e28 (2024)
Stress-dependent condensate formation regulated by the ubiquitin-related modifier Urm1. Cell 6.
Journal Article
121 (34), e2411135121 (2024)
Protein folding: From physico-chemical rules and cellular machineries of protein quality control to AI solutions. Proceedings of the National Academy of Sciences of the United States of America 7.
Journal Article
436 (14), 168615 (2024)
Interplay of proteostasis capacity and Pprotein aggregation: Implications for cellular function and disease. Journal of Molecular Biology 8.
Journal Article
84 (10), pp. 1980 - 1994 (2024)
Autophagy preferentially degrades non-fibrillar polyQ aggregates. Molecular Cell 9.
Journal Article
: NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62. Nature Communications 14 (1), 8368 (2023)
10.
Journal Article
186 (15), pp. 3227 - 3244 (2023)
Mechanisms of readthrough mitigation reveal principles of GCN1-mediated translational quality control. Cell 11.
Journal Article
: The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system. Nature Communications 14 (1), 560 (2023)
12.
Journal Article
: Calmodulin regulates protease versus co-chaperone activity of a metacaspase. Cell Reports 42, 113372 (2023)
13.
Journal Article
82 (22), pp. 4290 - 4306 (2022)
Formation of toxic oligomers of polyQ-expanded Huntingtin by prion-mediated cross-seeding. Molecular Cell 14.
Journal Article
44 (7), e2100287 (2022)
The chaperone Clusterin in neurodegeneration-friend or foe? Bioessays 15.
Journal Article
: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. EMBO Reports 23 (6), e53890 (2022)
16.
Journal Article
40 (19), e107260 (2021)
Fluc-EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease. EMBO Journal 17.
Journal Article
10, e62718 (2021)
Multiple pathways of toxicity induced by c9orf72 dipeptide repeat aggregates and G(4)C(2) RNA in a cellular model. eLife 18.
Journal Article
: The Hsc70 disaggregation machinery removes monomer units directly from alpha-synuclein fibril ends. Nature Communications 12 (1), 5999 (2021)
19.
Journal Article
81 (20), pp. 4114 - 4115 (2021)
A new way of D/Ealing with protein misfolding. Molecular Cell 20.
Journal Article
: In situ architecture of neuronal alpha-Synuclein inclusions. Nature Communications 12 (1), 2110 (2021)