![Manajit Hayer-Hartl Manajit Hayer-Hartl](/6611879/header_image-1565167776.jpg?t=eyJ3aWR0aCI6ODQ4LCJmaWxlX2V4dGVuc2lvbiI6ImpwZyIsIm9ial9pZCI6NjYxMTg3OX0%3D--b180c95d55d36085e4abcd18c8a7d6f895d1f046)
Manajit Hayer-Hartl
Research Group Chaperonin-assisted Protein Folding
Protein Folding and Assembly, Rubisco, GroEL and GroES, Mass Spectrometry
Proteins can only fulfill their tasks in their correct three-dimensional structure. Cellular chaperones are responsible for the correct folding in the cell. However, they can also help scientists to artificially produce important proteins in the test tube. Manajit Hayer-Hartl and her research group "Chaperonin-mediated protein folding" have already succeeded in doing this for the key protein of photosynthesis "RuBisCO". The complex structure of RuBisCO (16 subunits) made it impossible to produce a functional version of the protein in the test tube. Using chaperones and helper proteins, the researchers have succeeded in producing a functional RuBisCO complex.