Infrastructure
Protein Expression
Kühner shakers for expression in E.coli
Temperature controlled room for baculovirus-infected insect cell expression
CO2-controlled incubators and shakers for mammalian cell expression
Biochemical and Functional Analyses
Various liquid chromatography systems (Äkta Primes, Purifiers and Avant)
Isotope lab for 32P-labeled-nucleotide-based activity assays
Dissection microscope and dedicated incubators/shakers for yeast genetics
Crystallisation
Robotics
Automatic setup of up to 2400 crystallization conditions with a Phoenix nanodispenser robot from Art Robbins InstrumentsOptimization of crystallization conditions using robotics
Xtal-Focus Imaging Stations
Xtal-Focus Imaging Stations (Leica/Zeiss microscopes coupled to Thermo Fischer robotic arm and carrousel)Storage of plates in vizualization systems in temperature controlled rooms (4°C, 10°C and 19°C)
In-house X-ray generator D8 Venture (Bruker)
In-house X-ray generator D8 Venture (Bruker), with the newly developed liquid metal jet X-ray source
D8-Venture
Biophysics
Analytical gel filtration
Analytical gel filtration on Waters HPLC coupled to Viskotek Static Light Scattering analyzer
Isothermal calorimeter