Publications of R. Timpl

Sasaki, T.; Takagi, J.; Giudici, C.; Yamada, Y.; Arikawa-Hirasawa, E.; Deutzmann, R.; Timpl, R.; Sonnenberg, A.; Bachinger, H. P.; Tonge, D.: Laminin-121-Recombinant expression and interactions with integrins. Matrix Biology 29 (6), pp. 484 - 493 (2010)

Piscaglia, F.; Dudas, J.; Knittel, T.; Di Rocco, P.; Kobold, D.; Saile, B.; Zocco, M. A.; Timpl, R.; Ramadori, G.: Expression of ECM proteins fibulin-1 and-2 in acute and chronic liver disease and in cultured rat liver cells. Cell and Tissue Research 337 (3), pp. 449 - 462 (2009)

Giudici, C.; Raynal, N.; Wiedemann, H.; Cabral, W. A.; Marini, J. C.; Timpl, R.; Bachinger, H. P.; Farndale, R. W.; Sasaki, T.; Tenni, R.: Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens. Journal of Biological Chemistry 283 (28), pp. 19551 - 19560 (2008)

Kabosova, A.; Azar, D. T.; Bannikov, G. A.; Campbell, K. P.; Durbeej, M.; Ghohestani, R. F.; Jones, J. C. R.; Kenney, M. C.; Koch, M.; Ninomiya, Y. et al.; Patton, B. L.; Paulsson, M.; Sado, Y.; Sage, E. H.; Sasaki, T.; Sorokin, L. M.; Steiner-Champliaud, M. F.; Sun, T. T.; SundarRaj, N.; Timpl, R.; Virtanen, I.; Ljubimov, A. V.: Compositional differences between infant and adult human corneal basement membranes. Investigative Ophthalmology & Visual Science 48 (11), pp. 4989 - 4999 (2007)

Kvist, A. J.; Johnson, A. E.; Morgelin, M.; Gustafsson, E.; Bengtsson, E.; Lindblom, K.; Aszodi, A.; Fässler, R.; Sasaki, T.; Timpl, R. et al.; Aspberg, A.: Chondroitin sulfate perlecan enhances collagen fibril formation - Implications for perlecan chondrodysplasias. Journal of Biological Chemistry 281 (44), pp. 33127 - 33139 (2006)

Schmidt, A.; Wenzel, D.; Thorey, I.; Sasaki, T.; Hescheler, J.; Timpl, R.; Addicks, K.; Werner, S.; Fleischmann, B. K.; Bloch, W.: Endostatin influences endothelial morphology via the activated ERK1/2-kinase endothelial morphology and signal transduction. Microvascular Research 71 (3), pp. 152 - 162 (2006)

Sasaki, T.; Knyazev, P. G.; Clout, N. J.; Cheburkin, Y.; Göhring, W.; Ullrich, A.; Timpl, R.; Hohenester, E.: Structural basis for Gas6-Axl signalling. EMBO Journal 25 (1), pp. 80 - 87 (2006)

Kadoya, K.; Sasaki, T.; Kostka, G.; Timpl, R.; Matsuzaki, K.; Kumagai, N.; Sakai, L. Y.; Nishiyama, T.; Amano, S.: Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis. British Journal of Dermatology 153 (3), pp. 607 - 612 (2005)

Kanagawa, M.; Michele, D. E.; Satz, J. S.; Barresi, R.; Kusano, H.; Sasaki, T.; Timpl, R.; Henry, M. D.; Campbell, K. P.: Disruption of perlecan binding and matrix assembly by post-translational or genetic disruption of dystroglycan function. FEBS Letters 579 (21), pp. 4792 - 4796 (2005)

Gersdorff, N.; Kohfeldt, E.; Sasaki, T.; Timpl, R.; Miosge, N.: Laminin gamma 3 chain binds to nidogen and is located in murine basement membranes. Journal of Biological Chemistry 280 (23), pp. 22146 - 22153 (2005)

Scheele, S.; Falk, M.; Franzen, A.; Ellin, F.; Ferletta, M.; Lonai, P.; Andersson, B.; Timpl, R.; Forsberg, E.; Ekblom, P.: Laminin alpha 1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly. Proceedings of the National Academy of Sciences of the United States of America 102 (5), pp. 1502 - 1506 (2005)

Tiedemann, K.; Sasaki, T.; Gustafson, E.; Göhring, W.; Bätge, B.; Notbohm, H.; Timpl, R.; Wedel, T.; Schlötzer-Schrehardt, U.; Reinhardt, D.: Microfibrils at basement membrane zones interact with perlecan via fibrillin-1. Journal of Biological Chemistry 280, pp. 11404 - 11412 (2005)

Olsson, A. K.; Johansson, I.; Akerud, H.; Einarsson, B.; Christofferson, R.; Sasaki, T.; Timpl, R.; Claesson-Welsh, L.: The minimal active domain of endostatin is a heparin-binding motif that mediates inhibition of tumor vascularization. Cancer Research 64 (24), pp. 9012 - 9017 (2004)

Schmidt, A.; Wenzel, D.; Ferring, I.; Kazemi, S.; Sasaki, T.; Hescheler, J.; Timpl, R.; Addicks, K.; Fleischmann, B. K.; Bloch, W.: Influence of endostatin on embryonic vasculo- and angiogenesis. Developmental Dynamics 230 (3), pp. 468 - 480 (2004)

Day, J. M.; Olin, A. I.; Murdoch, A. D.; Canfield, A.; Sasaki, T.; Timpl, R.; Hardingham, T. E.; Aspberg, A.: Alternative splicing in the aggrecan G3 domain influences binding interactions with tenascin-C and other extracellular matrix proteins. Journal of Biological Chemistry 279 (13), pp. 12511 - 12518 (2004)

Meng, X. M.; Klement, J. F.; Lepen, D. A.; Birk, D. E.; Sasaki, T.; Timpl, R.; Uitto, J.; Pulkkinen, L.: Targeted inactivation of murine laminin γ2-chain gene recapitulates human junctional epidermolysis bullosa. Journal of Investigative Dermatology 121 (4), pp. 720 - 731 (2003)

Wizemann, H.; Garbe, J. H. O.; Friedrich, M. V. K.; Timpl, R.; Sasaki, T.; Hohenester, E.: Distinct requirements for heparin and α-dystroglycan binding revealed by structure-based mutagenesis of the laminin α2 LG4-LG5 domain pair. Journal of Molecular Biology 332 (3), pp. 635 - 642 (2003)

Timpl, R.; Sasaki, T.; Kostka, G.; Chu, M. L.: Fibulins: A versatile family of extracellular matrix proteins. Nature Reviews Molecular Cell Biology 4 (6), pp. 479 - 489 (2003)

Ferletta, M.; Kikkawa, Y.; Yu, H.; Talts, J. F.; Durbeej, M.; Sonnenberg, A.; Timpl, R.; Campbell, K. P.; Ekblom, P.; Genersch, E.: Opposing roles of integrin alpha 6A beta 1 and dystroglycan in laminin-mediated extracellular signal-regulated kinase activation. Molecular Biology of the Cell 14 (5), pp. 2088 - 2103 (2003)

Markova, D.; Zou, Y. Q.; Ringpfeil, F.; Sasaki, T.; Kostka, G.; Timpl, R.; Uitto, J.; Chu, M. L.: Genetic heterogeneity of cutis laxa: A heterozygous tandem duplication within the fibulin-5 (FBLN5) gene. American Journal of Human Genetics 72 (4), pp. 998 - 1004 (2003)