Publications of Sven Klumpe

Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoelz, B.; Ronchi, P.; Oorschot, V.; Brandstetter, M.; Yeroslaviz, A.; Briggs, J. A. G. et al.; Brennecke, J.; Beck, M.; Plitzko, J. M.: In-cell structure and snapshots of copia retrotransposons in intact tissue by cryoelectron tomography. Cell (2025)

Schiotz, O. H.; Klumpe, S.; Plitzko, J. M.; Kaiser, C. J. O.: Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues. Biochemical Society Transactions 52 (6), pp. 2415 - 2425 (2024)

Schiotz, O. H.; Kaiser, C. J. O.; Klumpe, S.; Morado, D. R.; Poege, M.; Schneider, J.; Beck, F.; Klebl, D. P.; Thompson, C.; Plitzko, J. M.: Serial Lift-Out: Sampling the molecular anatomy of whole organisms. Nature Methods 21 (9), pp. 1684 - 1692 (2024)

McCafferty, C. L.; Klumpe, S.; Amaro, R. E.; Kukulski, W.; Collinson, L.; Engel, B. D.: Integrating cellular electron microscopy with multimodal data to explore biology across space and time. Cell 187 (3), pp. 563 - 584 (2024)

Hung, K. Y. S.; Klumpe, S.; Eisele, M. R.; Elsasser, S.; Tian, G.; Sun, S.; Moroco, J. A.; Cheng, T. C.; Joshi, T.; Seibel, T. et al.; Van Dalen, D.; Feng, X.-H.; Lu, Y.; Ovaa, H.; Engen, J. R.; Lee, B.-H.; Rudack, T.; Sakata, E.; Finley, D.: Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nature Communications 13 (1), 838 (2022)

Khavnekar, S.; Vrbovská, V.; Zaoralová, M.; Kelley, R.; Beck, F.; Klumpe, S.; Kotecha, A.; Plitzko, J.; Erdmann, P. S.: Optimizing Cryo-FIB Lamellas for sub-5Å in situ Structural Biology. bioRxiv: the preprint server for biology (2022)

Klumpe, S.; Kuba, J.; Schioetz, O. H.; Erdmann, P. S.; Rigort, A.; Plitzko, J. M.: Recent Advances in Gas Injection System-Free Cryo-FIB Lift-Out Transfer for Cryo-Electron Tomography of Multicellular Organisms and Tissues. Microscopy Today 30, pp. 42 - 47 (2022)

Erdmann, P. S.; Hou, Z.; Klumpe, S.; Khavnekar, S.; Beck, F.; Wilfling, F.; Plitzko, J. M.; Baumeister, W.: In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Nature Communications 12 (1), 5364 (2021)

Gupta, T. K.; Klumpe, S.; Gries, K.; Heinz, S.; Wietrzynski, W.; Ohnishi, N.; Niemeyer, J.; Spaniol, B.; Schaffer, M.; Rast, A. et al.; Ostermeier, M.; Strauss, M.; Plitzko, J. M.; Baumeister, W.; Rudack, T.; Sakamoto, W.; Nickelsen, J.; Schuller, J. M.; Schroda, M.; Engel, B. D.: Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity. Cell 184 (14), pp. 3643 - 3659.e23 (2021)

Klumpe, S.; Fung, H. K. H.; Goetz, S. K.; Zagoriy, I.; Hampoelz, B.; Zhang, X.; Erdmann, P. S.; Baumbach, J.; Mueller, C. W.; Beck, M. et al.; Plitzko, J. M.; Mahamid, J.: A modular platform for automated cryo-FIB workflows. eLife 10, e70506 (2021)

Liu, Z.; Gao, J.; Cui, Y.; Klumpe, S.; Xiang, Y.; Erdmann, P. S.; Jiang, L.: Membrane imaging in the plant endomembrane system. Plant Physiology 185 (3), pp. 562 - 576 (2021)

Tacke, S.; Erdmann, P.; Wang, Z.; Klumpe, S.; Grange, M.; Plitzko, J.; Raunser, S.: A streamlined workflow for automated cryo focused ion beam milling. Journal of Structural Biology 213 (3), 107743 (2021)

Zinzula, L.; Basquin, J.; Bohn, S.; Beck, F.; Klumpe, S.; Pfeifer, G.; Nagy, I.; Bracher, A.; Hartl, F. U.; Baumeister, W.: High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2 acute respiratory syndrome coronavirus 2. Biochemical and Biophysical Research Communications 538, pp. 54 - 62 (2021)

Zinzula, L.; Beck, F.; Klumpe, S.; Bohn, S.; Pfeifer, G.; Bollschweiler, D.; Nagy, I.; Plitzko, J. M.; Baumeister, W.: Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex. Journal of Structural Biology 213 (3), 107750 (2021)

Klumpe, S.: Cryo-FIB development from unicellular to multicellular organisms - from VIPP1 to copia. Dissertation, Technische Universität München, School of Natural Sciences, München (2024)

Klumpe, S.: Integrative Structural Biology: Understanding Protein Complexes. Master, Technische Universität München, Fak. Chemie, München (2019)

Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoetz, B.; Ronchi, P.; Yeroslaviz, A.; Briggs, J. A. G.; Brennecke, J.; Beck, M. et al.; Plitzko, J. M.: In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography. bioRxiv: the preprint server for biology (2024)

Sachweh, J.; Börmel, M.; Klumpe, S.; Becker, A.; Taniguchi, R.; Kubańska, M. A.; Pintschovius, V.; Kaindl, E.; Plitzko, J. M.; Wilfling, F. et al.; Beck, M.; Hampoelz, B.: The small GTPase Ran defines Nuclear Pore Complex Asymmetry. bioRxiv: the preprint server for biology (2024)