Publications of Sebastian Kostrhon

Horn-Ghetko, D.; Hopf, L. V. M.; Tripathi-Giesgen, I.; Du, J.; Kostrhon, S.; Tung Vu, D.; Beier, V.; Steigenberger, B.; Prabu, J. R.; Stier, L. et al.; Bruss, E. M.; Mann, M.; Xiong, Y.; Schulman, B. A.: Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature Structural & Molecular Biology 31 (7), pp. 1083 - 1094 (2024)

Berrocal, D. A. P. A.; Vishwanatha, T. M.; Horn-Ghetko, D.; Botsch, J. J.; Hehl, L. A.; Kostrhon, S.; Misra, M.; Dikic, I.; Geurink, P. P.; van Dam, H. et al.; Schulman, B. A.; Mulder, M. P. C.: A Pro-Fluorescent Ubiquitin-Based Probe to Monitor Cysteine-Based E3 Ligase Activity. Angewandte Chemie International Edition 62 (32), e202303319 (2023)

Kostrhon, S.; Prabu, J. R.; Baek, K.; Horn-Ghetko, D.; Gronau, S. v.; Klügel, M.; Basquin, J.; Alpi, A. F.; Schulman, B. A.: CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation. Nature Chemical Biology 17 (10), pp. 1075 - 1083 (2021)

Kostrhon, S.: Cryo-EM structure of CUL5-ARIH2 E3-E3 Ligase complex reveals novel allosteric NEDD8 mechanism. Dissertation, TUM, Fakultät für Chemie, München (2022)