Publications of R. Torka

Orfi, Z.; Waczek, F.; Baska, F.; Szabadkai, I.; Torka, R.; Hartmann, J.; Orfi, L.; Ullrich, A.: Novel members of quinoline compound family enhance insulin secretion in RIN-5AH beta cells and in rat pancreatic islet microtissue. Scientific Reports 7, 44073 (2017)

Baumann, C.; Ullrich, A.; Torka, R.: GAS6 expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance. Molecular oncology 11 (10), pp. 1430 - 1447 (2017)

Onken, J.; Torka, R.; Korsing, S.; Radke, J.; Krementeskaia, I.; Nieminen, M.; Bai, X.; Ullrich, A.; Heppner, F.; Vajkoczy, P.: Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo. OncoTarget 7 (9), pp. 9876 - 9889 (2016)

Baska, F.; Szabadkai, I.; Sipos, A.; Breza, N.; Szantai-Kis, C.; Kekesi, L.; Garamvoelgyi, R.; Nemes, Z.; Baska, F.; Neumann, L. et al.; Torka, R.; Ullrich, A.; Keri, G.; Orfi, L.: Pharmacophore and Binding Analysis of Known and Novel B-RAF Kinase Inhibitors. CURRENT MEDICINAL CHEMISTRY 21 (17), pp. 1938 - 1955 (2014)

Szokol, B.; Gyulavari, P.; Kurko, I.; Baska, F.; Szantai-Kis, C.; Greff, Z.; Örfi, Z.; Petak, I.; Penzes, K.; Torka, R. et al.; Ullrich, A.; Örfi, L.; Vantus, T.; Keri, G.: Discovery and Biological Evaluation of Novel Dual EGFR/c-Met Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS 5 (4), pp. 298 - 303 (2014)

Torka, R.; Penzes, K.; Gusenbauer, S.; Baumann, C.; Szabadkai, I.; Orfi, L.; Keri, G.; Ullrich, A.: Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy. NEOPLASIA 16 (4), pp. 301 - 318 (2014)

Paolino, M.; Choidas, A.; Wallner, S.; Pranjic, B.; Uribesalgo, I.; Loeser, S.; Jamieson, A. M.; Langdon, W. Y.; Ikeda, F.; Fededa, J. P. et al.; Cronin, S. J.; Nitsch, R.; Schultz-Fademrecht, C.; Eickhoff, J.; Menninger, S.; Unger, A.; Torka, R.; Gruber, T.; Hinterleitner, R.; Baier, G.; Wolf, D.; Ullrich, A.; Klebl, B. M.; Penninger, J. M.: The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. NATURE 507 (7493), pp. 508 - 512 (2014)

Penzes, K.; Baumann, C.; Szabadkai, I.; Orfi, L.; Keri, G.; Ullrich, A.; Torka, R.: Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells. CANCER BIOLOGY & THERAPY 15 (11), pp. 1571 - 1582 (2014)

Torka, R.; Penzes, K.; Baumann, C.; Gusenbauer, S.; Szabadkai, I.; Orfi, L.; Keri, G.; Ullrich, A.: Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors - suggestion of combination therapy. In EUROPEAN JOURNAL OF CANCER, 50 (Suppl. 5), 801, pp. S193 - S194. ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND (2014)