Publications of F. U. Hartl

Dragovic, Z.; Shomura, Y.; Tzvetkov, N.; Hartl, F. U.; Bracher, A.: Fes1p acts as a nucleotide exchange factor for the ribosome-associated molecular chaperone Ssb1p. Biological Chemistry 387 (12), pp. 1593 - 1600 (2006)

Kaiser, C. M.; Chang, H. C.; Agashe, V. R.; Lakshmipathy, S. K.; Etchells, S. A.; Hayer-Hartl, M.; Hartl, F. U.; Barral, J. M.: Real-time observation of trigger factor function on translating ribosomes. Nature 444 (7118), pp. 455 - 460 (2006)

Fonseca, R.; Vabulas, R. M.; Hartl, F. U.; Bonhoeffer, T.; Nagerl, U. V.: A balance of protein synthesis and proteasome-dependent degradation determines the maintenance of LTP. Neuron 52 (2), pp. 239 - 245 (2006)

Behrends, C.; Langer, C. A.; Boteva, R.; Böttcher, U. M.; Stemp, M. J.; Schaffar, G.; Rao, B. V.; Giese, A.; Kretzschmar, H.; Siegers, K. et al.; Hartl, F. U.: Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers. Molecular Cell 23 (6), pp. 887 - 897 (2006)

Dragovic, Z.; Broadley, S. A.; Shomura, Y.; Bracher, A.; Hartl, F. U.: Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s. EMBO Journal 25 (11), pp. 2519 - 2528 (2006)

Tang, Y. C.; Chang, H. C.; Roeben, A.; Wischnewski, D.; Wischnewski, N.; Kerner, M. J.; Hartl, F. U.; Hayer-Hartl, M.: Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein. Cell 125 (5), pp. 903 - 914 (2006)

Bracher, A.; Hartl, F. U.: Hsp90 structure: when two ends meet. Nature Structural & Molecular Biology 13 (6), pp. 478 - 480 (2006)

Roeben, A.; Kofler, C.; Nagy, I.; Nickell, S.; Hartl, F. U.; Bracher, A.: Crystal structure of an archaeal actin homolog. Journal of Molecular Biology 358 (1), pp. 145 - 156 (2006)

Boeddrich, A.; Gaumer, B.; Haacke, A.; Tzvetkov, N.; Albrecht, M.; Evert, B. O.; Muller, E. C.; Lurz, R.; Breuer, P.; Schugardt, N. et al.; Plassmann, S.; Xu, K. X.; Warrick, J. M.; Suopanki, J.; Wullner, U.; Frank, R.; Hartl, F. U.; Bonini, N. M.; Wanker, E. E.: An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO Journal 25 (7), pp. 1547 - 1558 (2006)

Haacke, A.; Broadley, S. A.; Boteva, R.; Tzvetkov, N.; Hartl, F. U.; Breuer, P.: Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3. Human Molecular Genetics 15 (4), pp. 555 - 568 (2006)

Tomic, S.; Johnson, A. E.; Hartl, F. U.; Etchells, S. A.: Exploring the capacity of trigger factor to function as a shield for ribosome bound polypeptide chains. FEBS Letters 580 (1), pp. 72 - 76 (2006)

Grallath, S.; Schwarz, J. P.; Böttcher, U. M. K.; Bracher, A.; Hartl, F. U.; Siegers, K.: L25 functions as a conserved ribosomal docking site shared by nascent chain-associated complex and signal-recognition particle. EMBO Reports 7 (1), pp. 78 - 84 (2006)

Vabulas, R. M.; Hartl, F. U.: Protein synthesis upon acute nutrient restriction relies on proteasome function. Science 310 (5756), pp. 1960 - 1963 (2005)

Chang, H. C.; Kaiser, C. M.; Hartl, F. U.; Barral, J. M.: De novo folding of GFP fusion proteins: High efficiency in eukaryotes but not in bacteria. Journal of Molecular Biology 353 (2), pp. 397 - 409 (2005)

Stemp, M. J.; Guha, S.; Hartl, F. U.; Barral, J. M.: Efficient production of native actin upon translation in a bacterial lysate supplemented with the eukaryotic chaperonin TRiC. Biological Chemistry 386 (8), pp. 753 - 757 (2005)

Kerner, M. J.; Naylor, D. J.; Ishihama, Y.; Maier, T.; Chang, H. C.; Stines, A. P.; Georgopoulos, C.; Frishman, D.; Hayer-Hartl, M.; Mann, M. et al.; Hartl, F. U.: Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli. Cell 122 (2), pp. 209 - 220 (2005)

Bertsch, U.; Winklhofer, K. F.; Hirschberger, T.; Bieschke, J.; Weber, P.; Hartl, F. U.; Tavan, P.; Tatzelt, J.; Kretzschmar, H. A.; Giese, A.: Single molecule analysis of protein aggregation and prions by SIFT. FEBS Journal 272 (Suppl. Suppl. 1), pp. 338 - 339 (2005)

Bertsch, U.; Winklhofer, K. F.; Hirschberger, T.; Bieschke, J.; Weber, P.; Hartl, F. U.; Tavan, P.; Tatzelt, J.; Kretzschmar, H. A.; Giese, A.: Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets. Journal of Virology 79 (12), pp. 7785 - 7791 (2005)

Kretzschmar, H. A.; Bertsch, U.; Winklhofer, K. F.; Hirschberger, T.; Bieschke, J.; Weber, P.; Hartl, F. U.; Tavan, P.; Tatzelt, J.; Giese, A.: Single molecule analysis of protein aggregation and prions by sift. Journal of Neuropathology and Experimental Neurology 64 (5), p. 441 - 441 (2005)

Bracher, A.; Hartl, F. U.: Towards a complete structure of Hsp90. Structure 13 (4), pp. 501 - 502 (2005)