Publications of Jürg Müller

Ciapponi, M.; Karlukova, E.; Schkölziger, S.; Benda, C.; Müller, J.: Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Nature Structural & Molecular Biology 31 (7), pp. 1023 - 1027 (2024)

Bonnet, J.; Boichenko, I.; Kalb, R.; Le Jeune, M.; Maltseva, S.; Pieropan, M.; Finkl, K.; Fierz, B.; Müller, J.: PR-DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub1, an antagonist of chromatin compaction. Genes & Development 36 (19-20), pp. 1046 - 1061 (2022)

Elizarev, P.; Finkl, K.; Müller, J.: Distinct requirements for Pho, Sfmbt, and Ino80 for cell survival in Drosophila. Genetics 219 (1), iyab096 (2021)

Finogenova, K.; Bonnet, J.; Poepsel, S.; Schäfer, I. B.; Finkl, K.; Schmid, K.; Litz, C.; Strauss, M.; Benda, C.; Müller, J.: Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. eLife 9, e61964 (2020)

Bonnet, J.; Lindeboom, R. G. H.; Pokrovsky, D.; Stricker, G.; Celik, M. H.; Rupp, R. A. W.; Gagneur, J.; Vermeulen, M.; Imhof, A.; Müller, J.: Quantification of Proteins and Histone Marks in Drosophila Embryos Reveals Stoichiometric Relationships Impacting Chromatin Regulation. DEVELOPMENTAL CELL 51 (5), pp. 632 - 644.e6 (2019)

Lee, Y.; Yoon, E.; Cho, S.; Schmähling, S.; Müller, J.; Song, J.-J.: Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop. Structure 27 (5), pp. 846 - 852.e3 (2019)

Copur, Ö.; Müller, J.: Histone Demethylase Activity of Utx Is Essential for Viability and Regulation of HOX Gene Expression in Drosophila. Genetics 208 (2), pp. 633 - 637 (2018)

Copur, Ö.; Gorchakov, A.; Finkl, K.; Kuroda, M. I.; Müller, J.: Sex-specific phenotypes of histone H4 point mutants establish dosage compensation as the critical function of H4K16 acetylation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 115 (52), pp. 13336 - 13341 (2018)

Schmähling, S.; Meiler, A.; Lee, Y.; Mohammed, A.; Finkl, K.; Tauscher, K.; Israel, L.; Wirth, M.; Philippou-Massier, J.; Blum, H. et al.; Habermann, B.; Imhof, A.; Song, J.-J.; Müller, J.: Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC. Development 145 (7), UNSP dev163808 (2018)

Laprell, F.; Finkl, K.; Müller, J.: Propagation of Polycomb-repressed chromatin requires sequence-specific recruitment to DNA. Science 356 (6333), pp. 85 - 88 (2017)

Choi, J.; Bachmann, A. L.; Tauscher, K.; Benda, C.; Fierz, B.; Müller, J.: DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation. Nature Structural and Molecular Biology 24, pp. 1039 - 1047 (2017)

Frey, F.; Sheahan, T.; Finkl, K.; Stoehr, G.; Mann, M.; Benda, C.; Müller, J.: Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC. Genes and Development 30 (9), pp. 1116 - 1127 (2016)

Gambetta, M. C.; Müller, J.: A critical perspective of the diverse roles of O-GlcNAc transferase in chromatin. CHROMOSOMA 124 (4), pp. 429 - 442 (2015)

Kassis, J. A.; Müller, J.: Transcription through Polycomb response elements does not induce a switch from repression to activation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112 (48), pp. 14755 - 14756 (2015)

Pengelly, A. R.; Kalb, R.; Finkl, K.; Müller, J.: Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation. GENES & DEVELOPMENT 29 (14), pp. 1487 - 1492 (2015)

Gambetta, M. C.; Müller, J.: O-GlcNAcylation Prevents Aggregation of the Polycomb Group Repressor Polyhomeotic. DEVELOPMENTAL CELL 31 (5), pp. 629 - 639 (2014)

Müller, J.; Müller, C. W.: STRUCTURAL BIOLOGY Enzyme-chromatin complex visualized. NATURE 514 (7524), pp. 572 - 573 (2014)

Kalb, R.; Latwiel, S.; Baymaz, H. I.; Jansen, P. W. T. C.; Müller, C. W.; Vermeulen, M.; Müller, J.: Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression. NATURE STRUCTURAL & MOLECULAR BIOLOGY 21 (6), pp. 569 - 571 (2014)

Pengelly, A. R.; Copur, Ö.; Jaeckle, H.; Herzig, A.; Müller, J.: A Histone Mutant Reproduces the Phenotype Caused by Loss of Histone-Modifying Factor Polycomb. SCIENCE 339 (6120), pp. 698 - 699 (2013)

Alfieri, C.; Gambetta, M. C.; Matos, R.; Glatt, S.; Sehr, P.; Fraterman, S.; Wilm, M.; Müller, J.; Müller, C. W.: Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements. GENES & DEVELOPMENT 27 (21), pp. 2367 - 2379 (2013)