Publications of N. A. Kairies

Prime, M. E.; Courtney, S. M.; Brookfield, F. A.; Marston, R. W.; Walker, V.; Warne, J.; Boyd, A. E.; Kairies, N. A.; von der Saal, W.; Limberg, A. et al.; Georges, G.; Engh, R. A.; Goller, B.; Rueger, P.; Rueth, M.: Phthalazinone Pyrazoles as Potent, Selective, and Orally Bioavailable Inhibitors of Aurora-A Kinase. Journal of Medicinal Chemistry 54 (1), pp. 312 - 319 (2011)

Breitenlechner, C. B.; Kairies, N. A.; Honold, K.; Scheiblich, S.; Koll, H.; Greiter, E.; Koch, S.; Schafer, W.; Huber, R.; Engh, R. A.: Crystal structures of active Src kinase domain complexes. Journal of Molecular Biology 353 (2), pp. 222 - 231 (2005)

Gerhardt, S.; Schott, A. K.; Kairies, N.; Cushman, M.; Illarionov, B.; Eisenreich, W.; Bacher, A.; Huber, R.; Steinbacher, S.; Fischer, M.: Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8- ribityllumazine. Structure 10 (10), pp. 1371 - 1381 (2002)

Riedl, S. J.; Fuentes-Prior, P.; Renatus, M.; Kairies, N.; Krapp, S.; Huber, R.; Salvesen, G. S.; Bode, W.: Structural basis for the activation of human procaspase-7. Proceedings of the National Academy of Sciences of the United States of America 98 (26), pp. 14790 - 14795 (2001)