Publications of Lukas M. Langer

Kögel, A.; Keidel, A.; Loukeri, M.-J.; Kuhn, C. C.; Langer, L. M.; Schäfer, I. B.; Conti, E.: Structural basis of mRNA decay by the human exosome–ribosome supercomplex. Nature 635 (8037), pp. 237 - 242 (2024)

Langer, L. M.; Kurscheidt, K.; Basquin, J.; Bonneau, F.; Iermak, I.; Basquin, C.; Conti, E.: UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2. Nucleic Acids Research 52 (10), pp. 6036 - 6048 (2024)

Langer, L. M.; Bonneau, F.; Gat, Y.; Conti, E.: Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. eLife 10, e72353 (2021)

Langer, L. M.; Gat, Y.; Bonneau, F.; Conti, E.: Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. ELIFE 9, e57127 (2020)

Lingaraju, M.; Johnsen, D.; Schlundt, A.; Langer, L. M.; Basquin, J.; Sattler, M.; Jensen, T. H.; Falk, S.; Conti, E.: The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs. Nature Communications 10, 3393 (2019)

Langer, L.: Substrate specificity and regulation of the human SMG1-8-9 kinase complex. Dissertation, Ludwig-Maximilians-Universität, Fakultät für Chemie und Pharmazie, München (2022)