Publikationen von P. Goettig

Weidensee, S.; Goettig, P.; Bertone, M.; Haas, D.; Magdolen, V.; Kiechle, M.; Meindl, A.; van Kuilenburg, A. B. P.; Gross, E.: A mild phenotype of dihydropyrimidine dehydrogenase deficiency and developmental retardation associated with a missense mutation affecting cofactor binding. Clinical Biochemistry 44 (8-9), S. 722 - 724 (2011)

Tochowicz, A.; Goettig, P.; Visse, R.; Shitomi, Y.; Maskos, K.; Nagase, H.; Bode, W.; Itoh, Y.: Crystal structure of MT1-MMP hemopexin domain: identification of the dimer interface. International Journal of Experimental Pathology 91 (6), S. A39 - A40 (2010)

Tochowicz, A.; Maskos, K.; Huber, R.; Oltenfreiter, R.; Dive, V.; Yiotakis, A.; Zanda, M.; Pourmotabbed, T.; Bode, W.; Goettig, P.: Corrigendum to "Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side Chain to Selectivity" (Journal of Molecular Biology, vol 371, pg 989, 2007). Journal of Molecular Biology 388 (4), S. 917 - 918 (2009)

Yoon, H.; Blaber, S. I.; Debela, M.; Goettig, P.; Scarisbrick, I. A.; Blaber, M.: A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15. Biological Chemistry (4), S. 373 - 377 (2009)

Wisniewska, M.; Goettig, P.; Maskos, K.; Belouski, E.; Winters, D.; Hecht, R.; Black, R.; Bode, W.: Structural determinants of the ADAM inhibition by TIMP-3: Crystal structure of the TACE-N-TIMP-3 complex. Journal of Molecular Biology 381 (5), S. 1307 - 1319 (2008)

Debela, M.; Beaufort, N.; Magdolen, V.; Schechter, N. M.; Craik, C. S.; Schmitt, M.; Bode, W.; Goettig, P.: Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7. Biological Chemistry 389 (6), S. 623 - 632 (2008)

Friedrich, R.; Riester, D.; Göttig, P.; Thurk, M.; Schwienhorst, A.; Bode, W.: Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue. European Journal of Medicinal Chemistry 43 (6), S. 1330 - 1335 (2008)

Barazza, A.; Gotz, M.; Cadamuro, S. A.; Goettig, P.; Willem, M.; Steuber, H.; Kohler, T.; Jestel, A.; Reinemer, P.; Renner, C. et al.; Bode, W.; Moroder, L.: Macrocyclic statine-based inhibitors of BACE-1. ChemBioChem 8 (17), S. 2078 - 2091 (2007)

Debela, M.; Goettig, P.; Magdolen, V.; Huber, R.; Schechter, N. M.; Bode, W.: Structural basis of the zinc inhibition of human tissue kallikrein 5. Journal of Molecular Biology 373 (4), S. 1017 - 1031 (2007)

Debela, M.; Hess, P.; Magdolen, V.; Schechter, N. M.; Steiner, T.; Huber, R.; Bode, W.; Goettig, P.: Chymotryptic specificity determinants in the 1.0 angstrom structure of the zinc-inhibited human tissue kallikrein 7. Proceedings of the National Academy of Sciences of the United States of America 104 (41), S. 16086 - 16091 (2007)

Tochowicz, A.; Maskos, K.; Huber, R.; Oltenfreiter, R.; Dive, V.; Yiotakis, A.; Zanda, M.; Bode, W.; Goettig, P.: Crystal structures of MMP-9 complexes with five inhibitors: Contribution of the flexible arg424 side-chain to selectivity. Journal of Molecular Biology 371 (4), S. 989 - 1006 (2007)

Debela, M.; Magdolen, V.; Grimminger, V.; Sommerhoff, C.; Messerschmidt, A.; Huber, R.; Friedrich, R.; Bode, W.; Goettig, P.: Crystal structures of human tissue kallikrein 4: Activity modulation by a specific zinc binding site. Journal of Molecular Biology 362 (5), S. 1094 - 1107 (2006)

Debela, M.; Magdolen, V.; Schechter, N.; Valachova, M.; Lottspeich, F.; Craik, C. S.; Choe, Y.; Bode, W.; Goettig, P.: Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences. Journal of Biological Chemistry 281 (35), S. 25678 - 25688 (2006)

Goettig, P.; Brandstetter, H.; Groll, M.; Göhring, W.; Konarev, P. V.; Svergun, D. I.; Huber, R.; Kim, J. S.: X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum. Journal of Biological Chemistry 280 (39), S. 33387 - 33396 (2005)

Kyrieleis, O. J. P.; Goettig, P.; Kiefersauer, R.; Huber, R.; Brandstetter, H.: Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations. Journal of Molecular Biology 349 (4), S. 787 - 800 (2005)

Azim, M. K.; Goehring, W.; Song, H. K.; Ramachandran, R.; Bochtler, M.; Goettig, P.: Characterization of the Hs1U chaperone affinity for Hs1V protease. Protein Science 14 (5), S. 1357 - 1362 (2005)

Goettig, P.; Groll, M.; Kim, J. S.; Huber, R.; Brandstetter, H.: Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism. EMBO Journal 21 (20), S. 5343 - 5352 (2002)

Brandstetter, H.; Kim, J. S.; Groll, M.; Göttig, P.; Huber, R.: Structural basis for the processive protein degradation by tricorn protease. Biological Chemistry 383 (7-8), S. 1157 - 1165 (2002)