The so-called Holliday structure has nothing to do with holidays or vacation, but is rather a term that describes a complex crossover of similar DNA strings. Researcher Robin Holliday proposed this structure of genetic information in the 1960s. It occurs in DNA repair processes in our cells or during the formation of egg and sperm cells when paternal and maternal genetic information are combined. As reported by the journal eLife, scientists from the Max Planck Institute of Biochemistry in Martinsried have decoded the structure of the GEN1 protein that can undo this crossover, much like a molecular master tailor, by cutting the DNA with the highest precision in the correct place.
more