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Press Page Brenda Schulman
The department of Molecular Machines and Signaling was established in July 2017. We focus on understanding how ubiquitin (UB) and UB-like protein modifications direct extraordinary changes in the fates of their targets, such as altering stability, subcellular localization, interactions, or conformation.
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The vision for the department is to combine biochemical reconstitution, structure, enzymology, chemistry, protein design, cell biology and genetics – along with other cutting-edge technologies in collaboration with close colleagues (Especially in neighboring departments) – in an integrated and circular process, with continuous flow of information between methodologies.