Publications of Andreas Bracher

Bracher, A.; Kozany, C.; Hähle, A.; Wild, P.; Zacharias, M.; Hausch, F.: Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. JOURNAL OF MOLECULAR BIOLOGY 425 (22), pp. 4134 - 4144 (2013)

Wang, Y.; Kirschner, A.; Fabian, A.-K.; Gopalakrishnan, R.; Kress, C.; Hoogeland, B.; Koch, U.; Kozany, C.; Bracher, A.; Hausch, F.: Increasing the Efficiency of Ligands for FK506-Binding Protein 51 by Conformational Control. JOURNAL OF MEDICINAL CHEMISTRY 56 (10), pp. 3922 - 3935 (2013)

Rüßmann, F.; Stemp, M. J.; Mönkemeyer, L.; Etchells, S. A.; Bracher, A.; Hartl, F.-U.: Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109 (52), pp. 21208 - 21215 (2012)

Herzog, F.; Kahraman, A.; Boehringer, D.; Mak, R.; Bracher, A.; Walzthoeni, T.; Leitner, A.; Beck, M.; Hartl, F.-U.; Ban, N. et al.; Malmstroem, L.; Aebersold, R.: Structural Probing of a Protein Phosphatase 2A Network by Chemical Cross-Linking and Mass Spectrometry. SCIENCE 337 (6100), pp. 1348 - 1352 (2012)

Gopalakrishnan, R.; Kozany, C.; Wang, Y. S.; Schneider, S.; Hoogeland, B.; Bracher, A.; Hausch, F.: Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52. Journal of Medicinal Chemistry 55 (9), pp. 4123 - 4131 (2012)

Leitner, A.; Joachimiak, L. A.; Bracher, A.; Mönkemeyer, L.; Walzthoeni, T.; Chen, B.; Pechmann, S.; Holmes, S.; Cong, Y.; Ma, B. X. et al.; Ludtke, S.; Chiu, W.; Hartl, F. U.; Aebersold, R.; Frydman, J.: The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT. Structure 20 (5), pp. 814 - 825 (2012)

Pathare, G. R.; Nagy, I.; Bohn, S.; Unverdorben, P.; Hubert, A.; Körner, R.; Nickell, S.; Lasker, K.; Sali, A.; Tamura, T. et al.; Nishioka, T.; Förster, F.; Baumeister, W.; Bracher, A.: The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together. Proceedings of the National Academy of Sciences of the United States of America 109 (1), pp. 149 - 154 (2012)

Stotz, M.; Mueller-Cajar, O.; Ciniawsky, S.; Wendler, P.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Structure of green-type Rubisco activase from tobacco. Nature Structural & Molecular Biology 18 (12), pp. 1366 - 1370 (2011)

Mueller-Cajar, O.; Stotz, M.; Wendler, P.; Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Structure and function of the AAA(+) protein CbbX, a red-type Rubisco activase. Nature 479 (7372), pp. 194 - 199 (2011)

Gupta, R.; Kasturi, P.; Bracher, A.; Loew, C.; Zheng, M.; Villella, A.; Garza, D.; Hartl, F. U.; Raychaudhuri, S.: Firefly luciferase mutants as sensors of proteome stress. Nature Methods 8 (10), pp. 879 - 886 (2011)

Bracher, A.; Kozany, C.; Thost, A. K.; Hausch, F.: Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. Abstracts of the IXth International Congress of the Interdisciplinary AGNP-TDM Task Force, p. A9 - A9 (2011)

Gopalakrishnan, R.; Kozany, C.; Hoogeland, B.; Bracher, A.; Hausch, F.: FKBP ligands. Abstracts of the IXth International Congress of the Interdisciplinary AGNP-TDM Task Force, p. A38 - A38 (2011)

Bracher, A.; Starling-Windhof, A.; Hartl, F. U.; Hayer-Hartl, M.: Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco. Nature Structural & Molecular Biology 18 (8), pp. 875 - 880 (2011)

Hartl, F. U.; Bracher, A.; Hayer-Hartl, M.: Molecular chaperones in protein folding and proteostasis. Nature 475 (7356), pp. 324 - 332 (2011)

Bracher, A.; Kozany, C.; Thost, A. K.; Hausch, F.: Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. Acta Crystallographica Section D-Biological Crystallography 67, pp. 549 - 559 (2011)

Polier, S.; Hartl, F. U.; Bracher, A.: Interaction of the Hsp110 Molecular Chaperones from S. cerevisiae with Substrate Protein. Journal of Molecular Biology 401 (5), pp. 696 - 707 (2010)

Liu, C. M.; Young, A. L.; Starling-Windhof, A.; Bracher, A.; Saschenbrecker, S.; Rao, B. V.; Rao, K. V.; Berninghausen, O.; Mielke, T.; Hartl, F. U. et al.; Beckmann, R.; Hayer-Hartl, M.: Coupled chaperone action in folding and assembly of hexadecameric Rubisco. Nature 463 (7278), pp. 197 - 202 (2010)

Polier, S.; Dragovic, Z.; Hartl, F. U.; Bracher, A.: Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding. Cell 133 (6), pp. 1068 - 1079 (2008)

Saschenbrecker, S.; Bracher, A.; Rao, K. V.; Rao, B. V.; Hartl, F. U.; Hayer-Hartl, M.: Structure and function of RbcX, an assembly chaperone for hexadecameric rubisco. Cell 129 (6), pp. 1189 - 1200 (2007)

Roeben, A.; Plitzko, J. M.; Körner, R.; Böttcher, U. M. K.; Siegers, K.; Hayer-Hartl, M.; Bracher, A.: Structural basis for subunit assembly in UDP-glucose pyrophosphorylase from Saccharomyces cerevisiae. Journal of Molecular Biology 364, pp. 551 - 560 (2006)