Press Page Karl Duderstadt
Research in our group is focused on the molecular mechanisms that ensure accurate chromosome replication and organization. We develop novel single-molecule imaging approaches to characterize dynamic intermediates formed during these processes. Our long-term objective is to study the interplay between chromosome organization and replication to understand how barriers integral to chromosome architecture are overcome.
To support this effort, the group is organized into teams focused in different areas: development of novel imaging methods, characterization of complexes critical for chromosome organization, and DNA replication mechanism.