Publikationen von R. Timpl

Ahrens, T.; Lambert, M.; Pertz, O.; Sasaki, T.; Schulthess, T.; Mege, R. M.; Timpl, R.; Engel, J.: Homoassociation of VE-cadherin follows a mechanism common to "classical" cadherins. Journal of Molecular Biology 325 (4), S. 733 - 742 (2003)

Wiberg, C.; Heinegard, D.; Wenglen, C.; Timpl, R.; Morgelin, M.: Biglycan organizes collagen VI into hexagonal-like networks resembling tissue structures. Journal of Biological Chemistry 277 (51), S. 49120 - 49126 (2002)

Kreuger, J.; Matsumoto, T.; Vanwildemeersch, M.; Sasaki, T.; Timpl, R.; Claesson-Welsh, L.; Spillmann, D.; Lindahl, U.: Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function. EMBO Journal 21 (23), S. 6303 - 6311 (2002)

Sasaki, T.; Knyazev, P. G.; Cheburkin, Y.; Göhring, W.; Tisi, D.; Ullrich, A.; Timpl, R.; Hohenester, E.: Crystal structure of a C-terminal fragment of growth arrest- specific protein Gas6 - Receptor tyrosine kinase activation by laminin G-like domains. Journal of Biological Chemistry 277 (46), S. 44164 - 44170 (2002)

Miosge, N.; Sasaki, T.; Timpl, R.: Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice. Matrix Biology 21 (7), S. 611 - 621 (2002)

Salmivirta, K.; Talts, J. F.; Olsson, M.; Sasaki, T.; Timpl, R.; Ekblom, P.: Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens. Experimental Cell Research 279 (2), S. 188 - 201 (2002)

Schymeinsky, J.; Nedbal, S.; Miosge, N.; Poschl, E.; Rao, C.; Beier, D. R.; Skarnes, W. C.; Timpl, R.; Bader, B. L.: Gene structure and functional analysis of the mouse nidogen-2 gene: Nidogen-2 is not essential for basement membrane formation in mice. Molecular and Cellular Biology 22 (19), S. 6820 - 6830 (2002)

Rattenholl, A.; Pappano, W. N.; Koch, M.; Keene, D. R.; Kadler, K. E.; Sasaki, T.; Timpl, R.; Burgeson, R. E.; Greenspan, D. S.; Bruckner-Tuderman, L.: Proteinases of the bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen. Journal of Biological Chemistry 277 (29), S. 26372 - 26378 (2002)

Tu, H. M.; Sasaki, T.; Snellman, A.; Göhring, W.; Pirila, P.; Timpl, R.; Pihlajaniemi, T.: The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin. Journal of Biological Chemistry 277 (25), S. 23092 - 23099 (2002)

Willem, M.; Miosge, N.; Halfter, W.; Smyth, N.; Jannetti, I.; Burghart, E.; Timpl, R.; Mayer, U.: Specific ablation of the nidogen-binding site in the laminin gamma 1 chain interferes with kidney and lung development. Development 129 (11), S. 2711 - 2722 (2002)

Than, M. E.; Henrich, S.; Huber, R.; Ries, A.; Mann, K.; Kühn, K.; Timpl, R.; Bourenkov, G. P.; Bartunik, H. D.; Bode, W.: The 1.9-angstrom crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link. Proceedings of the National Academy of Sciences of the United States of America 99 (10), S. 6607 - 6612 (2002)

Hellstern, S.; Sasaki, T.; Fauser, C.; Lustig, A.; Timpl, R.; Engel, J.: Functional studies on recombinant domains of Mac-2-binding protein. Journal of Biological Chemistry 277 (18), S. 15690 - 15696 (2002)

Sasaki, T.; Giltay, R.; Talts, U.; Timpl, R.; Talts, J. F.: Expression and distribution of laminin alpha 1 and alpha 2 chains in embryonic and adult mouse tissues: An immunochemical approach. Experimental Cell Research 275 (2), S. 185 - 199 (2002)

Bengtsson, E.; Morgelin, M.; Sasaki, T.; Timpl, R.; Heinegard, D.; Aspberg, A.: The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor. Journal of Biological Chemistry 277 (17), S. 15061 - 15068 (2002)

Doi, M.; Thyboll, J.; Kortesmaa, J.; Jansson, K.; Iivanainen, A.; Parvardeh, M.; Timpl, R.; Hedin, U.; Swedenborg, J.; Tryggvason, K.: Recombinant human laminin-10 (alpha 5,beta 1,gamma 1) - Production, purification, and migration-promoting activity on vascular endothelial cells. Journal of Biological Chemistry 277 (15), S. 12741 - 12748 (2002)

Garbe, J. H. O.; Göhring, W.; Mann, K.; Timpl, R.; Sasaki, T.: Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha 3B and alpha 5 chains. Biochemical Journal 362, S. 213 - 221 (2002)

Sasaki, T.; Hohenester, E.; Timpl, R.: Structure and function of collagen-derived endostatin inhibitors of angiogenesis. IUBMB Life 53 (2), S. 77 - 84 (2002)

Tunggal, L.; Ravaux, J.; Pesch, M.; Smola, H.; Krieg, T.; Gaill, F.; Sasaki, T.; Timpl, R.; Mauch, C.; Aumailley, M.: Defective laminin 5 processing in cylindroma cells. American Journal of Pathology 160 (2), S. 459 - 468 (2002)

Sasaki, T.; Mann, K.; Miner, J. H.; Miosge, N.; Timpl, R.: Domain IV of mouse laminin beta 1 and beta 2 chains - Structure, glycosaminoglycan modification and immunochemical analysis of tissue contents. European Journal of Biochemistry 269 (2), S. 431 - 442 (2002)

Sorensen, D. R.; Read, T. A.; Porwol, T.; Olsen, B. R.; Timpl, R.; Sasaki, T.; Iversen, P. O.; Benestad, H. B.; Sim, B. K. L.; Bjerkvig, R.: Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma. Neuro-Oncology 4 (1), S. 1 - 8 (2002)